LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|
MCF7 | A443654 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 584 | 4156 | 0.1405 | -0.2230 |
MCF7 | OSI-027 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1789 | 4156 | 0.4304 | 0.1895 |
MCF7 | XMD11-85h | 3.33 | uM | LJP6 | 72 | hr | 1235 | 3133 | 4156 | 0.7539 | 0.6498 |
MCF7 | HG-6-64-01 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 2586 | 4156 | 0.6222 | 0.4624 |
MCF7 | WH-4-025 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1388 | 4156 | 0.3341 | 0.0525 |
MCF7 | WZ-4-145 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1848 | 4156 | 0.4446 | 0.2097 |
MCF7 | XMD16-144 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1764 | 4156 | 0.4246 | 0.1812 |
MCF7 | Brivanib | 3.33 | uM | LJP5 | 72 | hr | 1235 | 3966 | 4156 | 0.9542 | 0.9349 |
MCF7 | Buparlisib | 3.33 | uM | LJP5 | 72 | hr | 1235 | 854 | 4156 | 0.2056 | -0.1304 |
MCF7 | BX-912 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1930 | 4156 | 0.4645 | 0.2379 |
MCF7 | Canertinib | 3.33 | uM | LJP6 | 72 | hr | 1235 | 2081 | 4156 | 0.5009 | 0.2897 |
MCF7 | Celastrol | 3.33 | uM | LJP6 | 72 | hr | 1235 | 830 | 4156 | 0.1999 | -0.1386 |
MCF7 | CGP60474 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 673 | 4156 | 0.1619 | -0.1926 |
MCF7 | CGP60474 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 514 | 4156 | 0.1238 | -0.2468 |
MCF7 | CHIR-99021 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 2493 | 4156 | 0.5998 | 0.4306 |
MCF7 | CP724714 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 3278 | 4156 | 0.7889 | 0.6996 |
MCF7 | CP466722 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 4230 | 4156 | 1.0178 | 1.0254 |
MCF7 | Crizotinib | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1243 | 4156 | 0.2991 | 0.0026 |
MCF7 | Momelotinib | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1785 | 4156 | 0.4296 | 0.1884 |
MCF7 | Dasatinib | 3.33 | uM | LJP5 | 72 | hr | 1235 | 972 | 4156 | 0.2340 | -0.0899 |
MCF7 | Dasatinib | 3.33 | uM | LJP6 | 72 | hr | 1235 | 916 | 4156 | 0.2204 | -0.1094 |
MCF7 | Dovitinib | 3.33 | uM | LJP5 | 72 | hr | 1235 | 2215 | 4156 | 0.5329 | 0.3354 |
MCF7 | Enzastaurin | 3.33 | uM | LJP5 | 72 | hr | 1235 | 3734 | 4156 | 0.8985 | 0.8556 |
MCF7 | Erlotinib | 3.33 | uM | LJP5 | 72 | hr | 1235 | 4324 | 4156 | 1.0404 | 1.0575 |
MCF7 | Foretinib | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1290 | 4156 | 0.3105 | 0.0189 |