LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 Dasatinib
0.04
uM
LJP6
 72
hr
 868 777 3486 0.2229 -0.0348
MDA-MB-231 Dovitinib
0.04
uM
LJP5
 72
hr
 868 2712 3486 0.7781 0.7045
MDA-MB-231 Enzastaurin
0.04
uM
LJP5
 72
hr
 868 3487 3486 1.0004 1.0005
MDA-MB-231 Erlotinib
0.04
uM
LJP5
 72
hr
 868 2901 3486 0.8323 0.7767
MDA-MB-231 Foretinib
0.04
uM
LJP5
 72
hr
 868 3236 3486 0.9284 0.9046
MDA-MB-231 R406
0.04
uM
LJP6
 72
hr
 868 3428 3486 0.9834 0.9778
MDA-MB-231 Pictilisib
0.04
uM
LJP6
 72
hr
 868 2501 3486 0.7174 0.6237
MDA-MB-231 Gefitinib
0.04
uM
LJP6
 72
hr
 868 4066 3486 1.1664 1.2216
MDA-MB-231 Geldanamycin
0.04
uM
LJP5
 72
hr
 868 1313 3486 0.3766 0.1699
MDA-MB-231 Geldanamycin
0.04
uM
LJP6
 72
hr
 868 1639 3486 0.4703 0.2947
MDA-MB-231 GSK1059615
0.04
uM
LJP5
 72
hr
 868 3825 3486 1.0972 1.1294
MDA-MB-231 GSK1059615
0.04
uM
LJP6
 72
hr
 868 3909 3486 1.1212 1.1614
MDA-MB-231 GSK1904529A
0.04
uM
LJP6
 72
hr
 868 2588 3486 0.7424 0.6570
MDA-MB-231 Omipalisib
0.04
uM
LJP6
 72
hr
 868 2095 3486 0.6011 0.4688
MDA-MB-231 GSK 690693
0.04
uM
LJP5
 72
hr
 868 2658 3486 0.7625 0.6837
MDA-MB-231 GW843682X
0.04
uM
LJP6
 72
hr
 868 2934 3486 0.8417 0.7892
MDA-MB-231 HG-5-113-01
0.04
uM
LJP5
 72
hr
 868 3097 3486 0.8884 0.8514
MDA-MB-231 HG-5-88-01
0.04
uM
LJP6
 72
hr
 868 2470 3486 0.7086 0.6119
MDA-MB-231 Imatinib
0.04
uM
LJP6
 72
hr
 868 3834 3486 1.0998 1.1329
MDA-MB-231 JNK-9L
0.04
uM
LJP6
 72
hr
 868 2621 3486 0.7518 0.6695
MDA-MB-231 JW-7-24-1
0.04
uM
LJP6
 72
hr
 868 2560 3486 0.7344 0.6463
MDA-MB-231 Lapatinib
0.04
uM
LJP6
 72
hr
 868 3009 3486 0.8632 0.8178
MDA-MB-231 LDN-193189
0.04
uM
LJP5
 72
hr
 868 3684 3486 1.0567 1.0755
MDA-MB-231 Linifanib
0.04
uM
LJP6
 72
hr
 868 3905 3486 1.1201 1.1599
MDA-MB-231 Linsitinib
0.04
uM
LJP5
 72
hr
 868 2600 3486 0.7460 0.6617