LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|
MDA-MB-231 | SB590885 | 0.04 | uM | LJP5 | 72 | hr | 868 | 3452 | 3486 | 0.9901 | 0.9869 |
MDA-MB-231 | PIK-93 | 0.04 | uM | LJP5 | 72 | hr | 868 | 3598 | 3486 | 1.0322 | 1.0429 |
MDA-MB-231 | KIN001-043 | 0.04 | uM | LJP6 | 72 | hr | 868 | 3394 | 3486 | 0.9735 | 0.9647 |
MDA-MB-231 | Alpelisib | 0.04 | uM | LJP5 | 72 | hr | 868 | 3540 | 3486 | 1.0155 | 1.0206 |
MDA-MB-231 | Luminespib | 0.04 | uM | LJP5 | 72 | hr | 868 | 1038 | 3486 | 0.2978 | 0.0650 |
MDA-MB-231 | A443654 | 0.04 | uM | LJP6 | 72 | hr | 868 | 1292 | 3486 | 0.3706 | 0.1619 |
MDA-MB-231 | OSI-027 | 0.04 | uM | LJP6 | 72 | hr | 868 | 3680 | 3486 | 1.0557 | 1.0742 |
MDA-MB-231 | XMD11-85h | 0.04 | uM | LJP6 | 72 | hr | 868 | 2646 | 3486 | 0.7591 | 0.6792 |
MDA-MB-231 | HG-6-64-01 | 0.04 | uM | LJP6 | 72 | hr | 868 | 3755 | 3486 | 1.0772 | 1.1028 |
MDA-MB-231 | WH-4-025 | 0.04 | uM | LJP5 | 72 | hr | 868 | 2822 | 3486 | 0.8094 | 0.7463 |
MDA-MB-231 | WZ-4-145 | 0.04 | uM | LJP6 | 72 | hr | 868 | 2653 | 3486 | 0.7611 | 0.6818 |
MDA-MB-231 | XMD16-144 | 0.04 | uM | LJP5 | 72 | hr | 868 | 1714 | 3486 | 0.4917 | 0.3232 |
MDA-MB-231 | Brivanib | 0.04 | uM | LJP5 | 72 | hr | 868 | 2841 | 3486 | 0.8149 | 0.7535 |
MDA-MB-231 | Buparlisib | 0.04 | uM | LJP5 | 72 | hr | 868 | 3829 | 3486 | 1.0985 | 1.1311 |
MDA-MB-231 | BX-912 | 0.04 | uM | LJP5 | 72 | hr | 868 | 3067 | 3486 | 0.8798 | 0.8400 |
MDA-MB-231 | Canertinib | 0.04 | uM | LJP6 | 72 | hr | 868 | 3831 | 3486 | 1.0989 | 1.1317 |
MDA-MB-231 | Celastrol | 0.04 | uM | LJP6 | 72 | hr | 868 | 3721 | 3486 | 1.0675 | 1.0899 |
MDA-MB-231 | CGP60474 | 0.04 | uM | LJP5 | 72 | hr | 868 | 2398 | 3486 | 0.6878 | 0.5843 |
MDA-MB-231 | CGP60474 | 0.04 | uM | LJP6 | 72 | hr | 868 | 870 | 3486 | 0.2495 | 0.0007 |
MDA-MB-231 | CHIR-99021 | 0.04 | uM | LJP6 | 72 | hr | 868 | 3091 | 3486 | 0.8866 | 0.8490 |
MDA-MB-231 | CP724714 | 0.04 | uM | LJP5 | 72 | hr | 868 | 2656 | 3486 | 0.7620 | 0.6831 |
MDA-MB-231 | CP466722 | 0.04 | uM | LJP5 | 72 | hr | 868 | 3815 | 3486 | 1.0943 | 1.1256 |
MDA-MB-231 | Crizotinib | 0.04 | uM | LJP5 | 72 | hr | 868 | 2483 | 3486 | 0.7122 | 0.6168 |
MDA-MB-231 | Momelotinib | 0.04 | uM | LJP5 | 72 | hr | 868 | 2772 | 3486 | 0.7951 | 0.7272 |
MDA-MB-231 | Dasatinib | 0.04 | uM | LJP5 | 72 | hr | 868 | 1648 | 3486 | 0.4728 | 0.2980 |