LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|
MDA-MB-231 | CP724714 | 0.37 | uM | LJP5 | 72 | hr | 868 | 2643 | 3486 | 0.7583 | 0.6781 |
MDA-MB-231 | CP466722 | 0.37 | uM | LJP5 | 72 | hr | 868 | 3509 | 3486 | 1.0066 | 1.0088 |
MDA-MB-231 | Crizotinib | 0.37 | uM | LJP5 | 72 | hr | 868 | 2400 | 3486 | 0.6884 | 0.5851 |
MDA-MB-231 | Momelotinib | 0.37 | uM | LJP5 | 72 | hr | 868 | 2590 | 3486 | 0.7429 | 0.6576 |
MDA-MB-231 | Dasatinib | 0.37 | uM | LJP5 | 72 | hr | 868 | 496 | 3486 | 0.1424 | -0.1420 |
MDA-MB-231 | Dasatinib | 0.37 | uM | LJP6 | 72 | hr | 868 | 545 | 3486 | 0.1563 | -0.1234 |
MDA-MB-231 | Dovitinib | 0.37 | uM | LJP5 | 72 | hr | 868 | 1891 | 3486 | 0.5425 | 0.3908 |
MDA-MB-231 | Enzastaurin | 0.37 | uM | LJP5 | 72 | hr | 868 | 3475 | 3486 | 0.9969 | 0.9959 |
MDA-MB-231 | Erlotinib | 0.37 | uM | LJP5 | 72 | hr | 868 | 3259 | 3486 | 0.9350 | 0.9134 |
MDA-MB-231 | Foretinib | 0.37 | uM | LJP5 | 72 | hr | 868 | 1463 | 3486 | 0.4196 | 0.2272 |
MDA-MB-231 | R406 | 0.37 | uM | LJP6 | 72 | hr | 868 | 3030 | 3486 | 0.8692 | 0.8258 |
MDA-MB-231 | Pictilisib | 0.37 | uM | LJP6 | 72 | hr | 868 | 2611 | 3486 | 0.7489 | 0.6657 |
MDA-MB-231 | Gefitinib | 0.37 | uM | LJP6 | 72 | hr | 868 | 3668 | 3486 | 1.0522 | 1.0695 |
MDA-MB-231 | Geldanamycin | 0.37 | uM | LJP5 | 72 | hr | 868 | 1240 | 3486 | 0.3558 | 0.1422 |
MDA-MB-231 | Geldanamycin | 0.37 | uM | LJP6 | 72 | hr | 868 | 1323 | 3486 | 0.3795 | 0.1737 |
MDA-MB-231 | GSK1059615 | 0.37 | uM | LJP5 | 72 | hr | 868 | 3113 | 3486 | 0.8929 | 0.8574 |
MDA-MB-231 | GSK1059615 | 0.37 | uM | LJP6 | 72 | hr | 868 | 3102 | 3486 | 0.8898 | 0.8533 |
MDA-MB-231 | GSK1904529A | 0.37 | uM | LJP6 | 72 | hr | 868 | 3091 | 3486 | 0.8866 | 0.8490 |
MDA-MB-231 | Omipalisib | 0.37 | uM | LJP6 | 72 | hr | 868 | 1278 | 3486 | 0.3667 | 0.1567 |
MDA-MB-231 | GSK 690693 | 0.37 | uM | LJP5 | 72 | hr | 868 | 3036 | 3486 | 0.8709 | 0.8281 |
MDA-MB-231 | GW843682X | 0.37 | uM | LJP6 | 72 | hr | 868 | 1558 | 3486 | 0.4470 | 0.2636 |
MDA-MB-231 | HG-5-113-01 | 0.37 | uM | LJP5 | 72 | hr | 868 | 2123 | 3486 | 0.6090 | 0.4794 |
MDA-MB-231 | HG-5-88-01 | 0.37 | uM | LJP6 | 72 | hr | 868 | 2445 | 3486 | 0.7014 | 0.6024 |
MDA-MB-231 | Imatinib | 0.37 | uM | LJP6 | 72 | hr | 868 | 3778 | 3486 | 1.0838 | 1.1116 |
MDA-MB-231 | JNK-9L | 0.37 | uM | LJP6 | 72 | hr | 868 | 1999 | 3486 | 0.5736 | 0.4322 |