LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 BI-2536
0.37
uM
LJP6
 72
hr
 868 1170 3486 0.3358 0.1156
MDA-MB-231 BMS345541
0.37
uM
LJP6
 72
hr
 868 3262 3486 0.9356 0.9143
MDA-MB-231 SNS-032
0.37
uM
LJP6
 72
hr
 868 771 3486 0.2213 -0.0368
MDA-MB-231 GDC-0980
0.37
uM
LJP5
 72
hr
 868 1880 3486 0.5393 0.3866
MDA-MB-231 NVP-AEW541
0.37
uM
LJP5
 72
hr
 868 3583 3486 1.0277 1.0369
MDA-MB-231 SB590885
0.37
uM
LJP5
 72
hr
 868 2772 3486 0.7951 0.7272
MDA-MB-231 PIK-93
0.37
uM
LJP5
 72
hr
 868 3735 3486 1.0715 1.0952
MDA-MB-231 KIN001-043
0.37
uM
LJP6
 72
hr
 868 3030 3486 0.8693 0.8259
MDA-MB-231 Alpelisib
0.37
uM
LJP5
 72
hr
 868 3413 3486 0.9790 0.9720
MDA-MB-231 Luminespib
0.37
uM
LJP5
 72
hr
 868 1067 3486 0.3061 0.0760
MDA-MB-231 A443654
0.37
uM
LJP6
 72
hr
 868 859 3486 0.2464 -0.0035
MDA-MB-231 OSI-027
0.37
uM
LJP6
 72
hr
 868 2835 3486 0.8133 0.7513
MDA-MB-231 XMD11-85h
0.37
uM
LJP6
 72
hr
 868 2817 3486 0.8080 0.7443
MDA-MB-231 HG-6-64-01
0.37
uM
LJP6
 72
hr
 868 2755 3486 0.7902 0.7207
MDA-MB-231 WH-4-025
0.37
uM
LJP5
 72
hr
 868 1345 3486 0.3858 0.1821
MDA-MB-231 WZ-4-145
0.37
uM
LJP6
 72
hr
 868 2918 3486 0.8371 0.7830
MDA-MB-231 XMD16-144
0.37
uM
LJP5
 72
hr
 868 1224 3486 0.3513 0.1362
MDA-MB-231 Brivanib
0.37
uM
LJP5
 72
hr
 868 2967 3486 0.8512 0.8019
MDA-MB-231 Buparlisib
0.37
uM
LJP5
 72
hr
 868 2791 3486 0.8005 0.7344
MDA-MB-231 BX-912
0.37
uM
LJP5
 72
hr
 868 2960 3486 0.8491 0.7991
MDA-MB-231 Canertinib
0.37
uM
LJP6
 72
hr
 868 3162 3486 0.9071 0.8762
MDA-MB-231 Celastrol
0.37
uM
LJP6
 72
hr
 868 2005 3486 0.5752 0.4343
MDA-MB-231 CGP60474
0.37
uM
LJP5
 72
hr
 868 695 3486 0.1995 -0.0659
MDA-MB-231 CGP60474
0.37
uM
LJP6
 72
hr
 868 808 3486 0.2318 -0.0230
MDA-MB-231 CHIR-99021
0.37
uM
LJP6
 72
hr
 868 2913 3486 0.8357 0.7813