LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 GW843682X
3.33
uM
LJP6
 72
hr
 868 1029 3486 0.2953 0.0617
MDA-MB-231 HG-5-113-01
3.33
uM
LJP5
 72
hr
 868 1179 3486 0.3382 0.1187
MDA-MB-231 HG-5-88-01
3.33
uM
LJP6
 72
hr
 868 2204 3486 0.6324 0.5105
MDA-MB-231 Imatinib
3.33
uM
LJP6
 72
hr
 868 3697 3486 1.0605 1.0806
MDA-MB-231 JNK-9L
3.33
uM
LJP6
 72
hr
 868 850 3486 0.2440 -0.0067
MDA-MB-231 JW-7-24-1
3.33
uM
LJP6
 72
hr
 868 1881 3486 0.5395 0.3869
MDA-MB-231 Lapatinib
3.33
uM
LJP6
 72
hr
 868 3373 3486 0.9677 0.9569
MDA-MB-231 LDN-193189
3.33
uM
LJP5
 72
hr
 868 1081 3486 0.3102 0.0814
MDA-MB-231 Linifanib
3.33
uM
LJP6
 72
hr
 868 3880 3486 1.1130 1.1505
MDA-MB-231 Linsitinib
3.33
uM
LJP5
 72
hr
 868 2739 3486 0.7856 0.7146
MDA-MB-231 Mitoxantrone
3.33
uM
LJP5
 72
hr
 868 668 3486 0.1917 -0.0763
MDA-MB-231 Mitoxantrone
3.33
uM
LJP6
 72
hr
 868 645 3486 0.1851 -0.0851
MDA-MB-231 MK2206
3.33
uM
LJP6
 72
hr
 868 2585 3486 0.7416 0.6559
MDA-MB-231 Neratinib
3.33
uM
LJP5
 72
hr
 868 1563 3486 0.4484 0.2655
MDA-MB-231 Nilotinib
3.33
uM
LJP5
 72
hr
 868 2376 3486 0.6817 0.5762
MDA-MB-231 Nintedanib
3.33
uM
LJP6
 72
hr
 868 2488 3486 0.7138 0.6189
MDA-MB-231 NU7441
3.33
uM
LJP5
 72
hr
 868 1978 3486 0.5675 0.4242
MDA-MB-231 Dactolisib
3.33
uM
LJP5
 72
hr
 868 1479 3486 0.4242 0.2333
MDA-MB-231 NVP-TAE684
3.33
uM
LJP6
 72
hr
 868 1419 3486 0.4072 0.2107
MDA-MB-231 Palbociclib
3.33
uM
LJP6
 72
hr
 868 1584 3486 0.4543 0.2734
MDA-MB-231 PD0325901
3.33
uM
LJP5
 72
hr
 868 941 3486 0.2699 0.0278
MDA-MB-231 PD0325901
3.33
uM
LJP6
 72
hr
 868 861 3486 0.2472 -0.0025
MDA-MB-231 PD173074
3.33
uM
LJP6
 72
hr
 868 3652 3486 1.0475 1.0632
MDA-MB-231 PD184352
3.33
uM
LJP5
 72
hr
 868 1861 3486 0.5340 0.3795
MDA-MB-231 Pelitinib
3.33
uM
LJP5
 72
hr
 868 1535 3486 0.4404 0.2548