LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 PF431396
3.33
uM
LJP5
 72
hr
 868 1354 3486 0.3886 0.1858
MDA-MB-231 PF477736
3.33
uM
LJP5
 72
hr
 868 1360 3486 0.3901 0.1879
MDA-MB-231 PF562271
3.33
uM
LJP6
 72
hr
 868 1385 3486 0.3973 0.1974
MDA-MB-231 PHA-665752
3.33
uM
LJP5
 72
hr
 868 3294 3486 0.9450 0.9268
MDA-MB-231 PHA-793887
3.33
uM
LJP6
 72
hr
 868 852 3486 0.2446 -0.0059
MDA-MB-231 PI103
3.33
uM
LJP6
 72
hr
 868 1987 3486 0.5699 0.4273
MDA-MB-231 PLX-4720
3.33
uM
LJP5
 72
hr
 868 2602 3486 0.7463 0.6622
MDA-MB-231 QL-X-138
3.33
uM
LJP6
 72
hr
 868 1947 3486 0.5586 0.4122
MDA-MB-231 QL-XII-47
3.33
uM
LJP6
 72
hr
 868 899 3486 0.2581 0.0120
MDA-MB-231 Radicicol
3.33
uM
LJP5
 72
hr
 868 1112 3486 0.3191 0.0933
MDA-MB-231 Radicicol
3.33
uM
LJP6
 72
hr
 868 1277 3486 0.3664 0.1563
MDA-MB-231 Seliciclib
3.33
uM
LJP5
 72
hr
 868 2624 3486 0.7528 0.6709
MDA-MB-231 Ruxolitinib
3.33
uM
LJP5
 72
hr
 868 3306 3486 0.9484 0.9312
MDA-MB-231 XL147
3.33
uM
LJP5
 72
hr
 868 3611 3486 1.0358 1.0477
MDA-MB-231 Saracatinib
3.33
uM
LJP6
 72
hr
 868 2238 3486 0.6420 0.5233
MDA-MB-231 Selumetinib
3.33
uM
LJP6
 72
hr
 868 1674 3486 0.4803 0.3080
MDA-MB-231 Sirolimus
3.33
uM
LJP6
 72
hr
 868 2839 3486 0.8143 0.7527
MDA-MB-231 Sorafenib
3.33
uM
LJP6
 72
hr
 868 2760 3486 0.7917 0.7226
MDA-MB-231 SU11274
3.33
uM
LJP5
 72
hr
 868 3127 3486 0.8970 0.8629
MDA-MB-231 Fedratinib
3.33
uM
LJP5
 72
hr
 868 975 3486 0.2798 0.0409
MDA-MB-231 TGX221
3.33
uM
LJP5
 72
hr
 868 2001 3486 0.5741 0.4329
MDA-MB-231 Torin1
3.33
uM
LJP6
 72
hr
 868 1210 3486 0.3472 0.1307
MDA-MB-231 Torin2
3.33
uM
LJP5
 72
hr
 868 1122 3486 0.3220 0.0972
MDA-MB-231 Tozasertib
3.33
uM
LJP5
 72
hr
 868 1128 3486 0.3235 0.0993
MDA-MB-231 Trametinib
3.33
uM
LJP5
 72
hr
 868 1155 3486 0.3313 0.1096