LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 TWS119
3.33
uM
LJP5
 72
hr
 868 2263 3486 0.6493 0.5330
MDA-MB-231 Vemurafenib
3.33
uM
LJP5
 72
hr
 868 2762 3486 0.7924 0.7236
MDA-MB-231 Withaferin A
3.33
uM
LJP5
 72
hr
 868 768 3486 0.2204 -0.0381
MDA-MB-231 Withaferin A
3.33
uM
LJP6
 72
hr
 868 675 3486 0.1938 -0.0735
MDA-MB-231 WYE-125132
3.33
uM
LJP6
 72
hr
 868 1617 3486 0.4639 0.2862
MDA-MB-231 WZ3105
3.33
uM
LJP5
 72
hr
 868 682 3486 0.1956 -0.0711
MDA-MB-231 XMD11-50
3.33
uM
LJP6
 72
hr
 868 1252 3486 0.3591 0.1466
MDA-MB-231 Y39983
3.33
uM
LJP6
 72
hr
 868 2074 3486 0.5951 0.4608
MDA-MB-231 YM 201636
3.33
uM
LJP5
 72
hr
 868 2657 3486 0.7623 0.6835
MDA-MB-231 ZSTK474
3.33
uM
LJP6
 72
hr
 868 2199 3486 0.6308 0.5084
MDA-MB-231 Afatinib
10.0
uM
LJP6
 72
hr
 868 732 3486 0.2101 -0.0519
MDA-MB-231 Sigma A6730
10.0
uM
LJP5
 72
hr
 868 1912 3486 0.5486 0.3989
MDA-MB-231 Alvocidib
10.0
uM
LJP6
 72
hr
 868 667 3486 0.1914 -0.0767
MDA-MB-231 AT-7519
10.0
uM
LJP6
 72
hr
 868 553 3486 0.1586 -0.1204
MDA-MB-231 AZD 5438
10.0
uM
LJP6
 72
hr
 868 655 3486 0.1880 -0.0813
MDA-MB-231 AZD-6482
10.0
uM
LJP5
 72
hr
 868 1260 3486 0.3615 0.1498
MDA-MB-231 AZD7762
10.0
uM
LJP6
 72
hr
 868 633 3486 0.1817 -0.0897
MDA-MB-231 AZD8055
10.0
uM
LJP6
 72
hr
 868 980 3486 0.2812 0.0429
MDA-MB-231 AZD8330
10.0
uM
LJP5
 72
hr
 868 1031 3486 0.2959 0.0625
MDA-MB-231 Barasertib
10.0
uM
LJP5
 72
hr
 868 1246 3486 0.3574 0.1443
MDA-MB-231 BI-2536
10.0
uM
LJP6
 72
hr
 868 1222 3486 0.3506 0.1353
MDA-MB-231 BMS345541
10.0
uM
LJP6
 72
hr
 868 758 3486 0.2174 -0.0421
MDA-MB-231 SNS-032
10.0
uM
LJP6
 72
hr
 868 782 3486 0.2244 -0.0328
MDA-MB-231 GDC-0980
10.0
uM
LJP5
 72
hr
 868 1437 3486 0.4124 0.2175
MDA-MB-231 NVP-AEW541
10.0
uM
LJP5
 72
hr
 868 1340 3486 0.3845 0.1805