LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 PI103
0.37
uM
LJP6
 72
hr
 868 2226 3486 0.6385 0.5186
MDA-MB-231 PLX-4720
0.37
uM
LJP5
 72
hr
 868 3495 3486 1.0025 1.0033
MDA-MB-231 QL-X-138
0.37
uM
LJP6
 72
hr
 868 2661 3486 0.7634 0.6850
MDA-MB-231 QL-XII-47
0.37
uM
LJP6
 72
hr
 868 1442 3486 0.4138 0.2194
MDA-MB-231 Radicicol
0.37
uM
LJP5
 72
hr
 868 1485 3486 0.4261 0.2359
MDA-MB-231 Radicicol
0.37
uM
LJP6
 72
hr
 868 1679 3486 0.4818 0.3100
MDA-MB-231 Seliciclib
0.37
uM
LJP5
 72
hr
 868 3061 3486 0.8780 0.8375
MDA-MB-231 Ruxolitinib
0.37
uM
LJP5
 72
hr
 868 3106 3486 0.8911 0.8550
MDA-MB-231 XL147
0.37
uM
LJP5
 72
hr
 868 3659 3486 1.0497 1.0662
MDA-MB-231 Saracatinib
0.37
uM
LJP6
 72
hr
 868 2384 3486 0.6840 0.5792
MDA-MB-231 Selumetinib
0.37
uM
LJP6
 72
hr
 868 1974 3486 0.5662 0.4224
MDA-MB-231 Sirolimus
0.37
uM
LJP6
 72
hr
 868 2974 3486 0.8532 0.8046
MDA-MB-231 Sorafenib
0.37
uM
LJP6
 72
hr
 868 2860 3486 0.8205 0.7610
MDA-MB-231 SU11274
0.37
uM
LJP5
 72
hr
 868 3611 3486 1.0358 1.0477
MDA-MB-231 Fedratinib
0.37
uM
LJP5
 72
hr
 868 3137 3486 0.9000 0.8668
MDA-MB-231 TGX221
0.37
uM
LJP5
 72
hr
 868 2555 3486 0.7329 0.6443
MDA-MB-231 Torin1
0.37
uM
LJP6
 72
hr
 868 1519 3486 0.4358 0.2487
MDA-MB-231 Torin2
0.37
uM
LJP5
 72
hr
 868 1099 3486 0.3152 0.0882
MDA-MB-231 Tozasertib
0.37
uM
LJP5
 72
hr
 868 1107 3486 0.3176 0.0914
MDA-MB-231 Trametinib
0.37
uM
LJP5
 72
hr
 868 1199 3486 0.3441 0.1266
MDA-MB-231 TWS119
0.37
uM
LJP5
 72
hr
 868 3464 3486 0.9936 0.9915
MDA-MB-231 Vemurafenib
0.37
uM
LJP5
 72
hr
 868 3247 3486 0.9313 0.9086
MDA-MB-231 Withaferin A
0.37
uM
LJP5
 72
hr
 868 2200 3486 0.6311 0.5088
MDA-MB-231 Withaferin A
0.37
uM
LJP6
 72
hr
 868 1918 3486 0.5503 0.4012
MDA-MB-231 WYE-125132
0.37
uM
LJP6
 72
hr
 868 1873 3486 0.5372 0.3838