LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 Mitoxantrone
0.04
uM
LJP5
 72
hr
 868 877 3486 0.2516 0.0034
MDA-MB-231 Mitoxantrone
0.04
uM
LJP6
 72
hr
 868 914 3486 0.2623 0.0177
MDA-MB-231 MK2206
0.04
uM
LJP6
 72
hr
 868 3488 3486 1.0005 1.0006
MDA-MB-231 Neratinib
0.04
uM
LJP5
 72
hr
 868 2654 3486 0.7614 0.6823
MDA-MB-231 Nilotinib
0.04
uM
LJP5
 72
hr
 868 3097 3486 0.8884 0.8514
MDA-MB-231 Nintedanib
0.04
uM
LJP6
 72
hr
 868 3852 3486 1.1049 1.1396
MDA-MB-231 NU7441
0.04
uM
LJP5
 72
hr
 868 3623 3486 1.0393 1.0523
MDA-MB-231 Dactolisib
0.04
uM
LJP5
 72
hr
 868 2027 3486 0.5815 0.4427
MDA-MB-231 NVP-TAE684
0.04
uM
LJP6
 72
hr
 868 3248 3486 0.9318 0.9092
MDA-MB-231 Palbociclib
0.04
uM
LJP6
 72
hr
 868 2707 3486 0.7765 0.7023
MDA-MB-231 PD0325901
0.04
uM
LJP5
 72
hr
 868 2123 3486 0.6090 0.4794
MDA-MB-231 PD0325901
0.04
uM
LJP6
 72
hr
 868 2204 3486 0.6322 0.5102
MDA-MB-231 PD173074
0.04
uM
LJP6
 72
hr
 868 4084 3486 1.1716 1.2285
MDA-MB-231 PD184352
0.04
uM
LJP5
 72
hr
 868 3587 3486 1.0289 1.0384
MDA-MB-231 Pelitinib
0.04
uM
LJP5
 72
hr
 868 3741 3486 1.0730 1.0972
MDA-MB-231 PF431396
0.04
uM
LJP5
 72
hr
 868 3329 3486 0.9550 0.9400
MDA-MB-231 PF477736
0.04
uM
LJP5
 72
hr
 868 2965 3486 0.8505 0.8009
MDA-MB-231 PF562271
0.04
uM
LJP6
 72
hr
 868 3236 3486 0.9283 0.9045
MDA-MB-231 PHA-665752
0.04
uM
LJP5
 72
hr
 868 3586 3486 1.0288 1.0383
MDA-MB-231 PHA-793887
0.04
uM
LJP6
 72
hr
 868 1112 3486 0.3192 0.0934
MDA-MB-231 PI103
0.04
uM
LJP6
 72
hr
 868 2869 3486 0.8230 0.7643
MDA-MB-231 PLX-4720
0.04
uM
LJP5
 72
hr
 868 3516 3486 1.0087 1.0116
MDA-MB-231 QL-X-138
0.04
uM
LJP6
 72
hr
 868 2476 3486 0.7103 0.6142
MDA-MB-231 QL-XII-47
0.04
uM
LJP6
 72
hr
 868 2392 3486 0.6863 0.5823
MDA-MB-231 Radicicol
0.04
uM
LJP5
 72
hr
 868 3698 3486 1.0607 1.0808