LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 Radicicol
0.04
uM
LJP6
 72
hr
 868 3982 3486 1.1422 1.1893
MDA-MB-231 Seliciclib
0.04
uM
LJP5
 72
hr
 868 3636 3486 1.0430 1.0573
MDA-MB-231 Ruxolitinib
0.04
uM
LJP5
 72
hr
 868 3160 3486 0.9066 0.8756
MDA-MB-231 XL147
0.04
uM
LJP5
 72
hr
 868 3749 3486 1.0754 1.1004
MDA-MB-231 Saracatinib
0.04
uM
LJP6
 72
hr
 868 3338 3486 0.9575 0.9435
MDA-MB-231 Selumetinib
0.04
uM
LJP6
 72
hr
 868 3237 3486 0.9287 0.9050
MDA-MB-231 Sirolimus
0.04
uM
LJP6
 72
hr
 868 2868 3486 0.8228 0.7641
MDA-MB-231 Sorafenib
0.04
uM
LJP6
 72
hr
 868 3447 3486 0.9889 0.9852
MDA-MB-231 SU11274
0.04
uM
LJP5
 72
hr
 868 3885 3486 1.1144 1.1524
MDA-MB-231 Fedratinib
0.04
uM
LJP5
 72
hr
 868 3697 3486 1.0604 1.0804
MDA-MB-231 TGX221
0.04
uM
LJP5
 72
hr
 868 2426 3486 0.6960 0.5953
MDA-MB-231 Torin1
0.04
uM
LJP6
 72
hr
 868 1971 3486 0.5655 0.4215
MDA-MB-231 Torin2
0.04
uM
LJP5
 72
hr
 868 1312 3486 0.3765 0.1698
MDA-MB-231 Tozasertib
0.04
uM
LJP5
 72
hr
 868 1053 3486 0.3021 0.0707
MDA-MB-231 Trametinib
0.04
uM
LJP5
 72
hr
 868 1088 3486 0.3122 0.0841
MDA-MB-231 TWS119
0.04
uM
LJP5
 72
hr
 868 3371 3486 0.9669 0.9559
MDA-MB-231 Vemurafenib
0.04
uM
LJP5
 72
hr
 868 3240 3486 0.9295 0.9062
MDA-MB-231 Withaferin A
0.04
uM
LJP5
 72
hr
 868 3875 3486 1.1116 1.1485
MDA-MB-231 Withaferin A
0.04
uM
LJP6
 72
hr
 868 3607 3486 1.0347 1.0462
MDA-MB-231 WYE-125132
0.04
uM
LJP6
 72
hr
 868 2273 3486 0.6522 0.5368
MDA-MB-231 WZ3105
0.04
uM
LJP5
 72
hr
 868 682 3486 0.1957 -0.0710
MDA-MB-231 XMD11-50
0.04
uM
LJP6
 72
hr
 868 3077 3486 0.8828 0.8439
MDA-MB-231 Y39983
0.04
uM
LJP6
 72
hr
 868 3238 3486 0.9288 0.9051
MDA-MB-231 YM 201636
0.04
uM
LJP5
 72
hr
 868 3606 3486 1.0344 1.0458
MDA-MB-231 ZSTK474
0.04
uM
LJP6
 72
hr
 868 3338 3486 0.9574 0.9433