LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 WZ3105
0.37
uM
LJP5
 72
hr
 868 735 3486 0.2108 -0.0508
MDA-MB-231 XMD11-50
0.37
uM
LJP6
 72
hr
 868 1932 3486 0.5543 0.4065
MDA-MB-231 Y39983
0.37
uM
LJP6
 72
hr
 868 2848 3486 0.8170 0.7563
MDA-MB-231 YM 201636
0.37
uM
LJP5
 72
hr
 868 3142 3486 0.9014 0.8687
MDA-MB-231 ZSTK474
0.37
uM
LJP6
 72
hr
 868 2729 3486 0.7828 0.7107
MDA-MB-231 Afatinib
1.11
uM
LJP6
 72
hr
 868 2626 3486 0.7533 0.6715
MDA-MB-231 Sigma A6730
1.11
uM
LJP5
 72
hr
 868 2611 3486 0.7491 0.6659
MDA-MB-231 Alvocidib
1.11
uM
LJP6
 72
hr
 868 659 3486 0.1890 -0.0799
MDA-MB-231 AT-7519
1.11
uM
LJP6
 72
hr
 868 722 3486 0.2073 -0.0556
MDA-MB-231 AZD 5438
1.11
uM
LJP6
 72
hr
 868 886 3486 0.2543 0.0071
MDA-MB-231 AZD-6482
1.11
uM
LJP5
 72
hr
 868 2355 3486 0.6757 0.5681
MDA-MB-231 AZD7762
1.11
uM
LJP6
 72
hr
 868 852 3486 0.2445 -0.0060
MDA-MB-231 AZD8055
1.11
uM
LJP6
 72
hr
 868 1340 3486 0.3845 0.1804
MDA-MB-231 AZD8330
1.11
uM
LJP5
 72
hr
 868 1009 3486 0.2895 0.0539
MDA-MB-231 Barasertib
1.11
uM
LJP5
 72
hr
 868 1221 3486 0.3503 0.1349
MDA-MB-231 BI-2536
1.11
uM
LJP6
 72
hr
 868 1219 3486 0.3496 0.1340
MDA-MB-231 BMS345541
1.11
uM
LJP6
 72
hr
 868 2372 3486 0.6805 0.5745
MDA-MB-231 SNS-032
1.11
uM
LJP6
 72
hr
 868 748 3486 0.2146 -0.0458
MDA-MB-231 GDC-0980
1.11
uM
LJP5
 72
hr
 868 1620 3486 0.4649 0.2874
MDA-MB-231 NVP-AEW541
1.11
uM
LJP5
 72
hr
 868 3410 3486 0.9783 0.9711
MDA-MB-231 SB590885
1.11
uM
LJP5
 72
hr
 868 2293 3486 0.6577 0.5442
MDA-MB-231 PIK-93
1.11
uM
LJP5
 72
hr
 868 3305 3486 0.9481 0.9309
MDA-MB-231 KIN001-043
1.11
uM
LJP6
 72
hr
 868 3156 3486 0.9054 0.8741
MDA-MB-231 Alpelisib
1.11
uM
LJP5
 72
hr
 868 3232 3486 0.9272 0.9031
MDA-MB-231 Luminespib
1.11
uM
LJP5
 72
hr
 868 1014 3486 0.2909 0.0558