LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 R406
3.33
uM
LJP6
 72
hr
 1235 3054 4156 0.7348 0.6227
MCF7 Pictilisib
3.33
uM
LJP6
 72
hr
 1235 1191 4156 0.2866 -0.0151
MCF7 Gefitinib
3.33
uM
LJP6
 72
hr
 1235 4423 4156 1.0642 1.0914
MCF7 Geldanamycin
3.33
uM
LJP5
 72
hr
 1235 1297 4156 0.3122 0.0213
MCF7 Geldanamycin
3.33
uM
LJP6
 72
hr
 1235 1242 4156 0.2988 0.0023
MCF7 GSK1059615
3.33
uM
LJP5
 72
hr
 1235 1063 4156 0.2559 -0.0588
MCF7 GSK1059615
3.33
uM
LJP6
 72
hr
 1235 1156 4156 0.2783 -0.0270
MCF7 GSK1904529A
3.33
uM
LJP6
 72
hr
 1235 1945 4156 0.4681 0.2431
MCF7 Omipalisib
3.33
uM
LJP6
 72
hr
 1235 1053 4156 0.2535 -0.0622
MCF7 GSK 690693
3.33
uM
LJP5
 72
hr
 1235 2231 4156 0.5369 0.3410
MCF7 GW843682X
3.33
uM
LJP6
 72
hr
 1235 1328 4156 0.3196 0.0318
MCF7 HG-5-113-01
3.33
uM
LJP5
 72
hr
 1235 1371 4156 0.3300 0.0467
MCF7 HG-5-88-01
3.33
uM
LJP6
 72
hr
 1235 1501 4156 0.3612 0.0909
MCF7 Imatinib
3.33
uM
LJP6
 72
hr
 1235 4335 4156 1.0432 1.0615
MCF7 JNK-9L
3.33
uM
LJP6
 72
hr
 1235 1064 4156 0.2560 -0.0587
MCF7 JW-7-24-1
3.33
uM
LJP6
 72
hr
 1235 1581 4156 0.3806 0.1186
MCF7 Lapatinib
3.33
uM
LJP6
 72
hr
 1235 3964 4156 0.9538 0.9342
MCF7 LDN-193189
3.33
uM
LJP5
 72
hr
 1235 2191 4156 0.5272 0.3272
MCF7 Linifanib
3.33
uM
LJP6
 72
hr
 1235 3842 4156 0.9246 0.8927
MCF7 Linsitinib
3.33
uM
LJP5
 72
hr
 1235 2187 4156 0.5263 0.3259
MCF7 Mitoxantrone
3.33
uM
LJP5
 72
hr
 1235 621 4156 0.1496 -0.2101
MCF7 Mitoxantrone
3.33
uM
LJP6
 72
hr
 1235 660 4156 0.1589 -0.1969
MCF7 MK2206
3.33
uM
LJP6
 72
hr
 1235 1414 4156 0.3403 0.0613
MCF7 Neratinib
3.33
uM
LJP5
 72
hr
 1235 2031 4156 0.4888 0.2725
MCF7 Nilotinib
3.33
uM
LJP5
 72
hr
 1235 4349 4156 1.0466 1.0662