LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | BI-2536 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 1434 | 3694 | 0.3883 | -0.0191 |
| SK-BR-3 | BMS345541 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 3870 | 3694 | 1.0478 | 1.0797 |
| SK-BR-3 | SNS-032 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 1006 | 3694 | 0.2724 | -0.2121 |
| SK-BR-3 | GDC-0980 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 1495 | 3694 | 0.4049 | 0.0085 |
| SK-BR-3 | NVP-AEW541 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 4052 | 3694 | 1.0970 | 1.1616 |
| SK-BR-3 | SB590885 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 4225 | 3694 | 1.1439 | 1.2398 |
| SK-BR-3 | PIK-93 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 4097 | 3694 | 1.1093 | 1.1820 |
| SK-BR-3 | KIN001-043 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 3490 | 3694 | 0.9449 | 0.9081 |
| SK-BR-3 | Alpelisib | 0.12 | uM | LJP5 | 72 | hr | 1476 | 3174 | 3694 | 0.8593 | 0.7656 |
| SK-BR-3 | Luminespib | 0.12 | uM | LJP5 | 72 | hr | 1476 | 1650 | 3694 | 0.4468 | 0.0784 |
| SK-BR-3 | A443654 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 1235 | 3694 | 0.3345 | -0.1087 |
| SK-BR-3 | OSI-027 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 2266 | 3694 | 0.6135 | 0.3561 |
| SK-BR-3 | XMD11-85h | 0.12 | uM | LJP6 | 72 | hr | 1476 | 2948 | 3694 | 0.7980 | 0.6635 |
| SK-BR-3 | HG-6-64-01 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 3681 | 3694 | 0.9967 | 0.9944 |
| SK-BR-3 | WH-4-025 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 3473 | 3694 | 0.9403 | 0.9005 |
| SK-BR-3 | WZ-4-145 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 2255 | 3694 | 0.6106 | 0.3513 |
| SK-BR-3 | XMD16-144 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 1397 | 3694 | 0.3782 | -0.0360 |
| SK-BR-3 | Brivanib | 0.12 | uM | LJP5 | 72 | hr | 1476 | 2912 | 3694 | 0.7885 | 0.6476 |
| SK-BR-3 | Buparlisib | 0.12 | uM | LJP5 | 72 | hr | 1476 | 3057 | 3694 | 0.8276 | 0.7127 |
| SK-BR-3 | BX-912 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 2994 | 3694 | 0.8106 | 0.6844 |
| SK-BR-3 | Canertinib | 0.12 | uM | LJP6 | 72 | hr | 1476 | 1565 | 3694 | 0.4237 | 0.0398 |
| SK-BR-3 | Celastrol | 0.12 | uM | LJP6 | 72 | hr | 1476 | 2882 | 3694 | 0.7803 | 0.6339 |
| SK-BR-3 | CGP60474 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 2041 | 3694 | 0.5525 | 0.2545 |
| SK-BR-3 | CGP60474 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 918 | 3694 | 0.2485 | -0.2520 |
| SK-BR-3 | CHIR-99021 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 2808 | 3694 | 0.7601 | 0.6004 |