LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | CP724714 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 2084 | 3694 | 0.5643 | 0.2742 |
| SK-BR-3 | CP466722 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 3985 | 3694 | 1.0788 | 1.1312 |
| SK-BR-3 | Crizotinib | 0.12 | uM | LJP5 | 72 | hr | 1476 | 3203 | 3694 | 0.8672 | 0.7787 |
| SK-BR-3 | Momelotinib | 0.12 | uM | LJP5 | 72 | hr | 1476 | 2925 | 3694 | 0.7919 | 0.6533 |
| SK-BR-3 | Dasatinib | 0.12 | uM | LJP5 | 72 | hr | 1476 | 3769 | 3694 | 1.0205 | 1.0341 |
| SK-BR-3 | Dasatinib | 0.12 | uM | LJP6 | 72 | hr | 1476 | 3361 | 3694 | 0.9098 | 0.8498 |
| SK-BR-3 | Dovitinib | 0.12 | uM | LJP5 | 72 | hr | 1476 | 2818 | 3694 | 0.7629 | 0.6049 |
| SK-BR-3 | Enzastaurin | 0.12 | uM | LJP5 | 72 | hr | 1476 | 4205 | 3694 | 1.1383 | 1.2304 |
| SK-BR-3 | Erlotinib | 0.12 | uM | LJP5 | 72 | hr | 1476 | 3317 | 3694 | 0.8980 | 0.8301 |
| SK-BR-3 | Foretinib | 0.12 | uM | LJP5 | 72 | hr | 1476 | 2627 | 3694 | 0.7113 | 0.5191 |
| SK-BR-3 | R406 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 3694 | 3694 | 1.0002 | 1.0003 |
| SK-BR-3 | Pictilisib | 0.12 | uM | LJP6 | 72 | hr | 1476 | 2106 | 3694 | 0.5701 | 0.2838 |
| SK-BR-3 | Gefitinib | 0.12 | uM | LJP6 | 72 | hr | 1476 | 2989 | 3694 | 0.8092 | 0.6822 |
| SK-BR-3 | Geldanamycin | 0.12 | uM | LJP5 | 72 | hr | 1476 | 1389 | 3694 | 0.3760 | -0.0396 |
| SK-BR-3 | Geldanamycin | 0.12 | uM | LJP6 | 72 | hr | 1476 | 1327 | 3694 | 0.3593 | -0.0674 |
| SK-BR-3 | GSK1059615 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 3675 | 3694 | 0.9948 | 0.9914 |
| SK-BR-3 | GSK1059615 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 2965 | 3694 | 0.8028 | 0.6715 |
| SK-BR-3 | GSK1904529A | 0.12 | uM | LJP6 | 72 | hr | 1476 | 3161 | 3694 | 0.8557 | 0.7596 |
| SK-BR-3 | Omipalisib | 0.12 | uM | LJP6 | 72 | hr | 1476 | 1425 | 3694 | 0.3859 | -0.0232 |
| SK-BR-3 | GSK 690693 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 2592 | 3694 | 0.7019 | 0.5033 |
| SK-BR-3 | GW843682X | 0.12 | uM | LJP6 | 72 | hr | 1476 | 2171 | 3694 | 0.5878 | 0.3133 |
| SK-BR-3 | HG-5-113-01 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 2848 | 3694 | 0.7712 | 0.6187 |
| SK-BR-3 | HG-5-88-01 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 2967 | 3694 | 0.8033 | 0.6723 |
| SK-BR-3 | Imatinib | 0.12 | uM | LJP6 | 72 | hr | 1476 | 3841 | 3694 | 1.0400 | 1.0666 |
| SK-BR-3 | JNK-9L | 0.12 | uM | LJP6 | 72 | hr | 1476 | 2715 | 3694 | 0.7352 | 0.5588 |