LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | JW-7-24-1 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 2887 | 3694 | 0.7816 | 0.6362 |
| SK-BR-3 | Lapatinib | 0.12 | uM | LJP6 | 72 | hr | 1476 | 1526 | 3694 | 0.4131 | 0.0222 |
| SK-BR-3 | LDN-193189 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 4191 | 3694 | 1.1346 | 1.2243 |
| SK-BR-3 | Linifanib | 0.12 | uM | LJP6 | 72 | hr | 1476 | 3871 | 3694 | 1.0480 | 1.0800 |
| SK-BR-3 | Linsitinib | 0.12 | uM | LJP5 | 72 | hr | 1476 | 2930 | 3694 | 0.7934 | 0.6557 |
| SK-BR-3 | Mitoxantrone | 0.12 | uM | LJP5 | 72 | hr | 1476 | 1596 | 3694 | 0.4322 | 0.0541 |
| SK-BR-3 | Mitoxantrone | 0.12 | uM | LJP6 | 72 | hr | 1476 | 1531 | 3694 | 0.4146 | 0.0248 |
| SK-BR-3 | MK2206 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 2946 | 3694 | 0.7977 | 0.6629 |
| SK-BR-3 | Neratinib | 0.12 | uM | LJP5 | 72 | hr | 1476 | 1374 | 3694 | 0.3721 | -0.0460 |
| SK-BR-3 | Nilotinib | 0.12 | uM | LJP5 | 72 | hr | 1476 | 3935 | 3694 | 1.0653 | 1.1088 |
| SK-BR-3 | Nintedanib | 0.12 | uM | LJP6 | 72 | hr | 1476 | 3786 | 3694 | 1.0251 | 1.0418 |
| SK-BR-3 | NU7441 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 3759 | 3694 | 1.0176 | 1.0293 |
| SK-BR-3 | Dactolisib | 0.12 | uM | LJP5 | 72 | hr | 1476 | 1762 | 3694 | 0.4772 | 0.1290 |
| SK-BR-3 | NVP-TAE684 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 2822 | 3694 | 0.7641 | 0.6070 |
| SK-BR-3 | Palbociclib | 0.12 | uM | LJP6 | 72 | hr | 1476 | 2997 | 3694 | 0.8115 | 0.6859 |
| SK-BR-3 | PD0325901 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 3370 | 3694 | 0.9124 | 0.8540 |
| SK-BR-3 | PD0325901 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 3553 | 3694 | 0.9620 | 0.9367 |
| SK-BR-3 | PD173074 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 4293 | 3694 | 1.1621 | 1.2701 |
| SK-BR-3 | PD184352 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 3786 | 3694 | 1.0250 | 1.0416 |
| SK-BR-3 | Pelitinib | 0.12 | uM | LJP5 | 72 | hr | 1476 | 2188 | 3694 | 0.5924 | 0.3209 |
| SK-BR-3 | PF431396 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 2696 | 3694 | 0.7299 | 0.5500 |
| SK-BR-3 | PF477736 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 1678 | 3694 | 0.4544 | 0.0911 |
| SK-BR-3 | PF562271 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 3704 | 3694 | 1.0028 | 1.0046 |
| SK-BR-3 | PHA-665752 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 4086 | 3694 | 1.1063 | 1.1771 |
| SK-BR-3 | PHA-793887 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 1583 | 3694 | 0.4287 | 0.0482 |