LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | GW843682X | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1355 | 3694 | 0.3670 | -0.0546 |
| SK-BR-3 | HG-5-113-01 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1323 | 3694 | 0.3581 | -0.0693 |
| SK-BR-3 | HG-5-88-01 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 2858 | 3694 | 0.7739 | 0.6233 |
| SK-BR-3 | Imatinib | 1.11 | uM | LJP6 | 72 | hr | 1476 | 3810 | 3694 | 1.0316 | 1.0526 |
| SK-BR-3 | JNK-9L | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1619 | 3694 | 0.4385 | 0.0645 |
| SK-BR-3 | JW-7-24-1 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 2476 | 3694 | 0.6703 | 0.4507 |
| SK-BR-3 | Lapatinib | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1571 | 3694 | 0.4255 | 0.0428 |
| SK-BR-3 | LDN-193189 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3658 | 3694 | 0.9904 | 0.9840 |
| SK-BR-3 | Linifanib | 1.11 | uM | LJP6 | 72 | hr | 1476 | 4083 | 3694 | 1.1054 | 1.1756 |
| SK-BR-3 | Linsitinib | 1.11 | uM | LJP5 | 72 | hr | 1476 | 2921 | 3694 | 0.7908 | 0.6515 |
| SK-BR-3 | Mitoxantrone | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1496 | 3694 | 0.4052 | 0.0090 |
| SK-BR-3 | Mitoxantrone | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1313 | 3694 | 0.3556 | -0.0735 |
| SK-BR-3 | MK2206 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 2446 | 3694 | 0.6622 | 0.4371 |
| SK-BR-3 | Neratinib | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1446 | 3694 | 0.3916 | -0.0136 |
| SK-BR-3 | Nilotinib | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3942 | 3694 | 1.0672 | 1.1120 |
| SK-BR-3 | Nintedanib | 1.11 | uM | LJP6 | 72 | hr | 1476 | 3201 | 3694 | 0.8667 | 0.7779 |
| SK-BR-3 | NU7441 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 2764 | 3694 | 0.7484 | 0.5809 |
| SK-BR-3 | Dactolisib | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1605 | 3694 | 0.4345 | 0.0579 |
| SK-BR-3 | NVP-TAE684 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 2530 | 3694 | 0.6850 | 0.4752 |
| SK-BR-3 | Palbociclib | 1.11 | uM | LJP6 | 72 | hr | 1476 | 2716 | 3694 | 0.7354 | 0.5592 |
| SK-BR-3 | PD0325901 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3128 | 3694 | 0.8470 | 0.7450 |
| SK-BR-3 | PD0325901 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 3037 | 3694 | 0.8222 | 0.7038 |
| SK-BR-3 | PD173074 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 4269 | 3694 | 1.1557 | 1.2594 |
| SK-BR-3 | PD184352 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3824 | 3694 | 1.0352 | 1.0586 |
| SK-BR-3 | Pelitinib | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1500 | 3694 | 0.4062 | 0.0108 |