LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | TGX221 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 2940 | 3694 | 0.7961 | 0.6602 |
| SK-BR-3 | Torin1 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 1523 | 3694 | 0.4123 | 0.0209 |
| SK-BR-3 | Torin2 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 1310 | 3694 | 0.3547 | -0.0750 |
| SK-BR-3 | Tozasertib | 0.04 | uM | LJP5 | 72 | hr | 1476 | 1200 | 3694 | 0.3250 | -0.1245 |
| SK-BR-3 | Trametinib | 0.04 | uM | LJP5 | 72 | hr | 1476 | 2426 | 3694 | 0.6567 | 0.4281 |
| SK-BR-3 | TWS119 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 3872 | 3694 | 1.0482 | 1.0803 |
| SK-BR-3 | Vemurafenib | 0.04 | uM | LJP5 | 72 | hr | 1476 | 4001 | 3694 | 1.0831 | 1.1384 |
| SK-BR-3 | Withaferin A | 0.04 | uM | LJP5 | 72 | hr | 1476 | 3835 | 3694 | 1.0382 | 1.0636 |
| SK-BR-3 | Withaferin A | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3774 | 3694 | 1.0216 | 1.0361 |
| SK-BR-3 | WYE-125132 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 1756 | 3694 | 0.4754 | 0.1260 |
| SK-BR-3 | WZ3105 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 1114 | 3694 | 0.3016 | -0.1636 |
| SK-BR-3 | XMD11-50 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 2726 | 3694 | 0.7379 | 0.5634 |
| SK-BR-3 | Y39983 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3281 | 3694 | 0.8882 | 0.8137 |
| SK-BR-3 | YM 201636 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 4029 | 3694 | 1.0907 | 1.1511 |
| SK-BR-3 | ZSTK474 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3090 | 3694 | 0.8367 | 0.7279 |
| SK-BR-3 | Afatinib | 0.12 | uM | LJP6 | 72 | hr | 1476 | 1324 | 3694 | 0.3585 | -0.0687 |
| SK-BR-3 | Sigma A6730 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 3064 | 3694 | 0.8294 | 0.7159 |
| SK-BR-3 | Alvocidib | 0.12 | uM | LJP6 | 72 | hr | 1476 | 1219 | 3694 | 0.3302 | -0.1159 |
| SK-BR-3 | AT-7519 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 1759 | 3694 | 0.4763 | 0.1275 |
| SK-BR-3 | AZD 5438 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 2832 | 3694 | 0.7668 | 0.6115 |
| SK-BR-3 | AZD-6482 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 3696 | 3694 | 1.0005 | 1.0009 |
| SK-BR-3 | AZD7762 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 1351 | 3694 | 0.3659 | -0.0564 |
| SK-BR-3 | AZD8055 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 1473 | 3694 | 0.3989 | -0.0014 |
| SK-BR-3 | AZD8330 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 2842 | 3694 | 0.7694 | 0.6157 |
| SK-BR-3 | Barasertib | 0.12 | uM | LJP5 | 72 | hr | 1476 | 1430 | 3694 | 0.3871 | -0.0211 |