LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | WZ3105 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 904 | 4156 | 0.2176 | -0.1133 |
| MCF7 | XMD11-50 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 2030 | 4156 | 0.4884 | 0.2721 |
| MCF7 | Y39983 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 3338 | 4156 | 0.8033 | 0.7201 |
| MCF7 | YM 201636 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 2946 | 4156 | 0.7089 | 0.5858 |
| MCF7 | ZSTK474 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1337 | 4156 | 0.3219 | 0.0350 |
| MCF7 | Afatinib | 3.33 | uM | LJP6 | 72 | hr | 1235 | 2283 | 4156 | 0.5495 | 0.3589 |
| MCF7 | Sigma A6730 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 2373 | 4156 | 0.5710 | 0.3895 |
| MCF7 | Alvocidib | 3.33 | uM | LJP6 | 72 | hr | 1235 | 542 | 4156 | 0.1305 | -0.2373 |
| MCF7 | AT-7519 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 893 | 4156 | 0.2149 | -0.1171 |
| MCF7 | AZD 5438 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 779 | 4156 | 0.1874 | -0.1563 |
| MCF7 | AZD-6482 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 2813 | 4156 | 0.6770 | 0.5404 |
| MCF7 | AZD7762 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1057 | 4156 | 0.2543 | -0.0611 |
| MCF7 | AZD8055 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1242 | 4156 | 0.2988 | 0.0023 |
| MCF7 | AZD8330 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 2321 | 4156 | 0.5586 | 0.3719 |
| MCF7 | Barasertib | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1601 | 4156 | 0.3854 | 0.1254 |
| MCF7 | BI-2536 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1395 | 4156 | 0.3357 | 0.0548 |
| MCF7 | BMS345541 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 975 | 4156 | 0.2347 | -0.0890 |
| MCF7 | SNS-032 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 579 | 4156 | 0.1393 | -0.2247 |
| MCF7 | GDC-0980 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1167 | 4156 | 0.2809 | -0.0233 |
| MCF7 | NVP-AEW541 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 2212 | 4156 | 0.5323 | 0.3345 |
| MCF7 | SB590885 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 4700 | 4156 | 1.1310 | 1.1864 |
| MCF7 | PIK-93 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 2438 | 4156 | 0.5868 | 0.4120 |
| MCF7 | KIN001-043 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 3437 | 4156 | 0.8271 | 0.7540 |
| MCF7 | Alpelisib | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1698 | 4156 | 0.4087 | 0.1586 |
| MCF7 | Luminespib | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1388 | 4156 | 0.3341 | 0.0525 |