LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Radicicol | 0.12 | uM | LJP6 | 72 | hr | 1235 | 1793 | 4156 | 0.4315 | 0.1910 |
| MCF7 | Seliciclib | 0.12 | uM | LJP5 | 72 | hr | 1235 | 4452 | 4156 | 1.0712 | 1.1013 |
| MCF7 | Ruxolitinib | 0.12 | uM | LJP5 | 72 | hr | 1235 | 3957 | 4156 | 0.9522 | 0.9319 |
| MCF7 | XL147 | 0.12 | uM | LJP5 | 72 | hr | 1235 | 4394 | 4156 | 1.0574 | 1.0817 |
| MCF7 | Saracatinib | 0.12 | uM | LJP6 | 72 | hr | 1235 | 2857 | 4156 | 0.6875 | 0.5553 |
| MCF7 | Selumetinib | 0.12 | uM | LJP6 | 72 | hr | 1235 | 3193 | 4156 | 0.7684 | 0.6705 |
| MCF7 | Sirolimus | 0.12 | uM | LJP6 | 72 | hr | 1235 | 2650 | 4156 | 0.6378 | 0.4846 |
| MCF7 | Sorafenib | 0.12 | uM | LJP6 | 72 | hr | 1235 | 3561 | 4156 | 0.8568 | 0.7962 |
| MCF7 | SU11274 | 0.12 | uM | LJP5 | 72 | hr | 1235 | 4784 | 4156 | 1.1512 | 1.2152 |
| MCF7 | Fedratinib | 0.12 | uM | LJP5 | 72 | hr | 1235 | 4228 | 4156 | 1.0174 | 1.0247 |
| MCF7 | TGX221 | 0.12 | uM | LJP5 | 72 | hr | 1235 | 3633 | 4156 | 0.8742 | 0.8210 |
| MCF7 | Torin1 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 1509 | 4156 | 0.3632 | 0.0938 |
| MCF7 | Torin2 | 0.12 | uM | LJP5 | 72 | hr | 1235 | 1160 | 4156 | 0.2792 | -0.0257 |
| MCF7 | Tozasertib | 0.12 | uM | LJP5 | 72 | hr | 1235 | 1383 | 4156 | 0.3328 | 0.0505 |
| MCF7 | Trametinib | 0.12 | uM | LJP5 | 72 | hr | 1235 | 2219 | 4156 | 0.5339 | 0.3368 |
| MCF7 | TWS119 | 0.12 | uM | LJP5 | 72 | hr | 1235 | 4177 | 4156 | 1.0052 | 1.0074 |
| MCF7 | Vemurafenib | 0.12 | uM | LJP5 | 72 | hr | 1235 | 4427 | 4156 | 1.0653 | 1.0930 |
| MCF7 | Withaferin A | 0.12 | uM | LJP5 | 72 | hr | 1235 | 3865 | 4156 | 0.9299 | 0.9003 |
| MCF7 | Withaferin A | 0.12 | uM | LJP6 | 72 | hr | 1235 | 3365 | 4156 | 0.8096 | 0.7291 |
| MCF7 | WYE-125132 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 1725 | 4156 | 0.4151 | 0.1678 |
| MCF7 | WZ3105 | 0.12 | uM | LJP5 | 72 | hr | 1235 | 827 | 4156 | 0.1990 | -0.1398 |
| MCF7 | XMD11-50 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 3303 | 4156 | 0.7947 | 0.7079 |
| MCF7 | Y39983 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 4182 | 4156 | 1.0062 | 1.0088 |
| MCF7 | YM 201636 | 0.12 | uM | LJP5 | 72 | hr | 1235 | 4254 | 4156 | 1.0237 | 1.0337 |
| MCF7 | ZSTK474 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 2292 | 4156 | 0.5516 | 0.3619 |