LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Mitoxantrone | 0.12 | uM | LJP5 | 72 | hr | 1235 | 1315 | 4156 | 0.3165 | 0.0274 |
| MCF7 | Mitoxantrone | 0.12 | uM | LJP6 | 72 | hr | 1235 | 1156 | 4156 | 0.2782 | -0.0271 |
| MCF7 | MK2206 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 2395 | 4156 | 0.5763 | 0.3971 |
| MCF7 | Neratinib | 0.12 | uM | LJP5 | 72 | hr | 1235 | 2830 | 4156 | 0.6811 | 0.5462 |
| MCF7 | Nilotinib | 0.12 | uM | LJP5 | 72 | hr | 1235 | 4440 | 4156 | 1.0685 | 1.0974 |
| MCF7 | Nintedanib | 0.12 | uM | LJP6 | 72 | hr | 1235 | 3521 | 4156 | 0.8472 | 0.7825 |
| MCF7 | NU7441 | 0.12 | uM | LJP5 | 72 | hr | 1235 | 4160 | 4156 | 1.0011 | 1.0015 |
| MCF7 | Dactolisib | 0.12 | uM | LJP5 | 72 | hr | 1235 | 1777 | 4156 | 0.4277 | 0.1857 |
| MCF7 | NVP-TAE684 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 1410 | 4156 | 0.3394 | 0.0600 |
| MCF7 | Palbociclib | 0.12 | uM | LJP6 | 72 | hr | 1235 | 2425 | 4156 | 0.5836 | 0.4074 |
| MCF7 | PD0325901 | 0.12 | uM | LJP5 | 72 | hr | 1235 | 2656 | 4156 | 0.6391 | 0.4865 |
| MCF7 | PD0325901 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 2490 | 4156 | 0.5991 | 0.4296 |
| MCF7 | PD173074 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 4427 | 4156 | 1.0652 | 1.0927 |
| MCF7 | PD184352 | 0.12 | uM | LJP5 | 72 | hr | 1235 | 3911 | 4156 | 0.9412 | 0.9163 |
| MCF7 | Pelitinib | 0.12 | uM | LJP5 | 72 | hr | 1235 | 4915 | 4156 | 1.1827 | 1.2600 |
| MCF7 | PF431396 | 0.12 | uM | LJP5 | 72 | hr | 1235 | 2184 | 4156 | 0.5255 | 0.3248 |
| MCF7 | PF477736 | 0.12 | uM | LJP5 | 72 | hr | 1235 | 2160 | 4156 | 0.5198 | 0.3167 |
| MCF7 | PF562271 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 3336 | 4156 | 0.8028 | 0.7194 |
| MCF7 | PHA-665752 | 0.12 | uM | LJP5 | 72 | hr | 1235 | 4759 | 4156 | 1.1451 | 1.2065 |
| MCF7 | PHA-793887 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 1381 | 4156 | 0.3324 | 0.0501 |
| MCF7 | PI103 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 2471 | 4156 | 0.5947 | 0.4233 |
| MCF7 | PLX-4720 | 0.12 | uM | LJP5 | 72 | hr | 1235 | 3969 | 4156 | 0.9551 | 0.9362 |
| MCF7 | QL-X-138 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 1647 | 4156 | 0.3964 | 0.1410 |
| MCF7 | QL-XII-47 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 1806 | 4156 | 0.4345 | 0.1954 |
| MCF7 | Radicicol | 0.12 | uM | LJP5 | 72 | hr | 1235 | 1760 | 4156 | 0.4235 | 0.1796 |