LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | PI103 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1223 | 4156 | 0.2943 | -0.0042 |
| MCF7 | PLX-4720 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 4186 | 4156 | 1.0073 | 1.0104 |
| MCF7 | QL-X-138 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1553 | 4156 | 0.3737 | 0.1087 |
| MCF7 | QL-XII-47 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 951 | 4156 | 0.2290 | -0.0971 |
| MCF7 | Radicicol | 1.11 | uM | LJP5 | 72 | hr | 1235 | 1587 | 4156 | 0.3818 | 0.1204 |
| MCF7 | Radicicol | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1626 | 4156 | 0.3912 | 0.1337 |
| MCF7 | Seliciclib | 1.11 | uM | LJP5 | 72 | hr | 1235 | 3527 | 4156 | 0.8486 | 0.7846 |
| MCF7 | Ruxolitinib | 1.11 | uM | LJP5 | 72 | hr | 1235 | 4302 | 4156 | 1.0352 | 1.0502 |
| MCF7 | XL147 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 4461 | 4156 | 1.0734 | 1.1045 |
| MCF7 | Saracatinib | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1688 | 4156 | 0.4061 | 0.1550 |
| MCF7 | Selumetinib | 1.11 | uM | LJP6 | 72 | hr | 1235 | 2833 | 4156 | 0.6817 | 0.5471 |
| MCF7 | Sirolimus | 1.11 | uM | LJP6 | 72 | hr | 1235 | 2650 | 4156 | 0.6377 | 0.4844 |
| MCF7 | Sorafenib | 1.11 | uM | LJP6 | 72 | hr | 1235 | 3680 | 4156 | 0.8854 | 0.8370 |
| MCF7 | SU11274 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 3896 | 4156 | 0.9376 | 0.9112 |
| MCF7 | Fedratinib | 1.11 | uM | LJP5 | 72 | hr | 1235 | 2443 | 4156 | 0.5878 | 0.4135 |
| MCF7 | TGX221 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 4179 | 4156 | 1.0057 | 1.0080 |
| MCF7 | Torin1 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1185 | 4156 | 0.2852 | -0.0171 |
| MCF7 | Torin2 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 1143 | 4156 | 0.2752 | -0.0314 |
| MCF7 | Tozasertib | 1.11 | uM | LJP5 | 72 | hr | 1235 | 1368 | 4156 | 0.3292 | 0.0454 |
| MCF7 | Trametinib | 1.11 | uM | LJP5 | 72 | hr | 1235 | 2286 | 4156 | 0.5501 | 0.3598 |
| MCF7 | TWS119 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 3874 | 4156 | 0.9321 | 0.9034 |
| MCF7 | Vemurafenib | 1.11 | uM | LJP5 | 72 | hr | 1235 | 4134 | 4156 | 0.9948 | 0.9925 |
| MCF7 | Withaferin A | 1.11 | uM | LJP5 | 72 | hr | 1235 | 1563 | 4156 | 0.3761 | 0.1122 |
| MCF7 | Withaferin A | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1337 | 4156 | 0.3219 | 0.0350 |
| MCF7 | WYE-125132 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1781 | 4156 | 0.4285 | 0.1868 |