LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | JW-7-24-1 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1666 | 4156 | 0.4009 | 0.1474 |
| MCF7 | Lapatinib | 1.11 | uM | LJP6 | 72 | hr | 1235 | 3799 | 4156 | 0.9142 | 0.8779 |
| MCF7 | LDN-193189 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 3862 | 4156 | 0.9293 | 0.8994 |
| MCF7 | Linifanib | 1.11 | uM | LJP6 | 72 | hr | 1235 | 4163 | 4156 | 1.0018 | 1.0026 |
| MCF7 | Linsitinib | 1.11 | uM | LJP5 | 72 | hr | 1235 | 2251 | 4156 | 0.5417 | 0.3478 |
| MCF7 | Mitoxantrone | 1.11 | uM | LJP5 | 72 | hr | 1235 | 1061 | 4156 | 0.2554 | -0.0596 |
| MCF7 | Mitoxantrone | 1.11 | uM | LJP6 | 72 | hr | 1235 | 988 | 4156 | 0.2377 | -0.0847 |
| MCF7 | MK2206 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1659 | 4156 | 0.3992 | 0.1450 |
| MCF7 | Neratinib | 1.11 | uM | LJP5 | 72 | hr | 1235 | 2436 | 4156 | 0.5862 | 0.4112 |
| MCF7 | Nilotinib | 1.11 | uM | LJP5 | 72 | hr | 1235 | 4146 | 4156 | 0.9977 | 0.9968 |
| MCF7 | Nintedanib | 1.11 | uM | LJP6 | 72 | hr | 1235 | 2119 | 4156 | 0.5100 | 0.3028 |
| MCF7 | NU7441 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 3783 | 4156 | 0.9103 | 0.8724 |
| MCF7 | Dactolisib | 1.11 | uM | LJP5 | 72 | hr | 1235 | 1371 | 4156 | 0.3300 | 0.0467 |
| MCF7 | NVP-TAE684 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1065 | 4156 | 0.2564 | -0.0581 |
| MCF7 | Palbociclib | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1794 | 4156 | 0.4317 | 0.1913 |
| MCF7 | PD0325901 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 2435 | 4156 | 0.5860 | 0.4108 |
| MCF7 | PD0325901 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 2251 | 4156 | 0.5417 | 0.3478 |
| MCF7 | PD173074 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 4692 | 4156 | 1.1291 | 1.1837 |
| MCF7 | PD184352 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 3287 | 4156 | 0.7910 | 0.7027 |
| MCF7 | Pelitinib | 1.11 | uM | LJP5 | 72 | hr | 1235 | 3706 | 4156 | 0.8919 | 0.8461 |
| MCF7 | PF431396 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 1436 | 4156 | 0.3457 | 0.0689 |
| MCF7 | PF477736 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 1768 | 4156 | 0.4256 | 0.1826 |
| MCF7 | PF562271 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1591 | 4156 | 0.3828 | 0.1218 |
| MCF7 | PHA-665752 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 4218 | 4156 | 1.0150 | 1.0214 |
| MCF7 | PHA-793887 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1207 | 4156 | 0.2905 | -0.0096 |