LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | CP724714 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 3304 | 4156 | 0.7950 | 0.7082 |
| MCF7 | CP466722 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 4687 | 4156 | 1.1277 | 1.1817 |
| MCF7 | Crizotinib | 1.11 | uM | LJP5 | 72 | hr | 1235 | 1641 | 4156 | 0.3949 | 0.1390 |
| MCF7 | Momelotinib | 1.11 | uM | LJP5 | 72 | hr | 1235 | 2804 | 4156 | 0.6747 | 0.5372 |
| MCF7 | Dasatinib | 1.11 | uM | LJP5 | 72 | hr | 1235 | 999 | 4156 | 0.2405 | -0.0808 |
| MCF7 | Dasatinib | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1065 | 4156 | 0.2564 | -0.0581 |
| MCF7 | Dovitinib | 1.11 | uM | LJP5 | 72 | hr | 1235 | 2849 | 4156 | 0.6856 | 0.5526 |
| MCF7 | Enzastaurin | 1.11 | uM | LJP5 | 72 | hr | 1235 | 3931 | 4156 | 0.9459 | 0.9230 |
| MCF7 | Erlotinib | 1.11 | uM | LJP5 | 72 | hr | 1235 | 4396 | 4156 | 1.0577 | 1.0821 |
| MCF7 | Foretinib | 1.11 | uM | LJP5 | 72 | hr | 1235 | 1412 | 4156 | 0.3398 | 0.0606 |
| MCF7 | R406 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 3733 | 4156 | 0.8983 | 0.8552 |
| MCF7 | Pictilisib | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1211 | 4156 | 0.2915 | -0.0081 |
| MCF7 | Gefitinib | 1.11 | uM | LJP6 | 72 | hr | 1235 | 4574 | 4156 | 1.1007 | 1.1433 |
| MCF7 | Geldanamycin | 1.11 | uM | LJP5 | 72 | hr | 1235 | 1371 | 4156 | 0.3299 | 0.0464 |
| MCF7 | Geldanamycin | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1452 | 4156 | 0.3494 | 0.0742 |
| MCF7 | GSK1059615 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 1668 | 4156 | 0.4014 | 0.1482 |
| MCF7 | GSK1059615 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1706 | 4156 | 0.4106 | 0.1614 |
| MCF7 | GSK1904529A | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1904 | 4156 | 0.4581 | 0.2289 |
| MCF7 | Omipalisib | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1194 | 4156 | 0.2874 | -0.0139 |
| MCF7 | GSK 690693 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 2108 | 4156 | 0.5074 | 0.2990 |
| MCF7 | GW843682X | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1433 | 4156 | 0.3448 | 0.0677 |
| MCF7 | HG-5-113-01 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 1446 | 4156 | 0.3479 | 0.0721 |
| MCF7 | HG-5-88-01 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1895 | 4156 | 0.4561 | 0.2261 |
| MCF7 | Imatinib | 1.11 | uM | LJP6 | 72 | hr | 1235 | 4431 | 4156 | 1.0661 | 1.0941 |
| MCF7 | JNK-9L | 1.11 | uM | LJP6 | 72 | hr | 1235 | 982 | 4156 | 0.2364 | -0.0865 |