LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Nintedanib | 10.0 | uM | LJP6 | 72 | hr | 513 | 9040 | 10401 | 0.8692 | 0.8624 |
| MCF 10A | NU7441 | 10.0 | uM | LJP5 | 72 | hr | 513 | 1002 | 10401 | 0.0964 | 0.0495 |
| MCF 10A | Dactolisib | 10.0 | uM | LJP5 | 72 | hr | 513 | 1157 | 10401 | 0.1112 | 0.0651 |
| MCF 10A | NVP-TAE684 | 10.0 | uM | LJP6 | 72 | hr | 513 | 863 | 10401 | 0.0830 | 0.0354 |
| MCF 10A | Palbociclib | 10.0 | uM | LJP6 | 72 | hr | 513 | 2395 | 10401 | 0.2303 | 0.1903 |
| MCF 10A | PD0325901 | 10.0 | uM | LJP5 | 72 | hr | 513 | 575 | 10401 | 0.0553 | 0.0062 |
| MCF 10A | PD0325901 | 10.0 | uM | LJP6 | 72 | hr | 513 | 398 | 10401 | 0.0383 | -0.0117 |
| MCF 10A | PD173074 | 10.0 | uM | LJP6 | 72 | hr | 513 | 2992 | 10401 | 0.2877 | 0.2507 |
| MCF 10A | PD184352 | 10.0 | uM | LJP5 | 72 | hr | 513 | 781 | 10401 | 0.0752 | 0.0271 |
| MCF 10A | Pelitinib | 10.0 | uM | LJP5 | 72 | hr | 513 | 516 | 10401 | 0.0497 | 0.0003 |
| MCF 10A | PF431396 | 10.0 | uM | LJP5 | 72 | hr | 513 | 592 | 10401 | 0.0569 | 0.0080 |
| MCF 10A | PF477736 | 10.0 | uM | LJP5 | 72 | hr | 513 | 600 | 10401 | 0.0577 | 0.0088 |
| MCF 10A | PF562271 | 10.0 | uM | LJP6 | 72 | hr | 513 | 589 | 10401 | 0.0567 | 0.0077 |
| MCF 10A | PHA-665752 | 10.0 | uM | LJP5 | 72 | hr | 513 | 684 | 10401 | 0.0658 | 0.0173 |
| MCF 10A | PHA-793887 | 10.0 | uM | LJP6 | 72 | hr | 513 | 567 | 10401 | 0.0545 | 0.0054 |
| MCF 10A | PI103 | 10.0 | uM | LJP6 | 72 | hr | 513 | 772 | 10401 | 0.0743 | 0.0262 |
| MCF 10A | PLX-4720 | 10.0 | uM | LJP5 | 72 | hr | 513 | 7135 | 10401 | 0.6860 | 0.6697 |
| MCF 10A | QL-X-138 | 10.0 | uM | LJP6 | 72 | hr | 513 | 363 | 10401 | 0.0349 | -0.0152 |
| MCF 10A | QL-XII-47 | 10.0 | uM | LJP6 | 72 | hr | 513 | 567 | 10401 | 0.0545 | 0.0054 |
| MCF 10A | Radicicol | 10.0 | uM | LJP5 | 72 | hr | 513 | 347 | 10401 | 0.0334 | -0.0168 |
| MCF 10A | Radicicol | 10.0 | uM | LJP6 | 72 | hr | 513 | 419 | 10401 | 0.0403 | -0.0095 |
| MCF 10A | Seliciclib | 10.0 | uM | LJP5 | 72 | hr | 513 | 1269 | 10401 | 0.1220 | 0.0764 |
| MCF 10A | Ruxolitinib | 10.0 | uM | LJP5 | 72 | hr | 513 | 6672 | 10401 | 0.6415 | 0.6229 |
| MCF 10A | XL147 | 10.0 | uM | LJP5 | 72 | hr | 513 | 4774 | 10401 | 0.4590 | 0.4309 |
| MCF 10A | Saracatinib | 10.0 | uM | LJP6 | 72 | hr | 513 | 716 | 10401 | 0.0689 | 0.0206 |