LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A Dasatinib
0.37
uM
LJP6
 72
hr
 513 525 10401 0.0505 0.0012
MCF 10A Dovitinib
0.37
uM
LJP5
 72
hr
 513 3966 10401 0.3813 0.3492
MCF 10A Enzastaurin
0.37
uM
LJP5
 72
hr
 513 9980 10401 0.9595 0.9574
MCF 10A Erlotinib
0.37
uM
LJP5
 72
hr
 513 2357 10401 0.2266 0.1865
MCF 10A Foretinib
0.37
uM
LJP5
 72
hr
 513 8179 10401 0.7864 0.7753
MCF 10A R406
0.37
uM
LJP6
 72
hr
 513 8786 10401 0.8447 0.8367
MCF 10A Pictilisib
0.37
uM
LJP6
 72
hr
 513 2168 10401 0.2085 0.1674
MCF 10A Gefitinib
0.37
uM
LJP6
 72
hr
 513 1020 10401 0.0981 0.0513
MCF 10A Geldanamycin
0.37
uM
LJP5
 72
hr
 513 539 10401 0.0519 0.0026
MCF 10A Geldanamycin
0.37
uM
LJP6
 72
hr
 513 507 10401 0.0488 -0.0006
MCF 10A GSK1059615
0.37
uM
LJP5
 72
hr
 513 2539 10401 0.2442 0.2049
MCF 10A GSK1059615
0.37
uM
LJP6
 72
hr
 513 2001 10401 0.1924 0.1505
MCF 10A GSK1904529A
0.37
uM
LJP6
 72
hr
 513 2532 10401 0.2434 0.2042
MCF 10A Omipalisib
0.37
uM
LJP6
 72
hr
 513 536 10401 0.0515 0.0023
MCF 10A GSK 690693
0.37
uM
LJP5
 72
hr
 513 9016 10401 0.8668 0.8599
MCF 10A GW843682X
0.37
uM
LJP6
 72
hr
 513 2003 10401 0.1926 0.1507
MCF 10A HG-5-113-01
0.37
uM
LJP5
 72
hr
 513 6915 10401 0.6649 0.6475
MCF 10A HG-5-88-01
0.37
uM
LJP6
 72
hr
 513 4095 10401 0.3937 0.3623
MCF 10A Imatinib
0.37
uM
LJP6
 72
hr
 513 10451 10401 1.0049 1.0051
MCF 10A JNK-9L
0.37
uM
LJP6
 72
hr
 513 3138 10401 0.3017 0.2655
MCF 10A JW-7-24-1
0.37
uM
LJP6
 72
hr
 513 8077 10401 0.7766 0.7650
MCF 10A Lapatinib
0.37
uM
LJP6
 72
hr
 513 8542 10401 0.8213 0.8120
MCF 10A LDN-193189
0.37
uM
LJP5
 72
hr
 513 9654 10401 0.9282 0.9244
MCF 10A Linifanib
0.37
uM
LJP6
 72
hr
 513 10979 10401 1.0556 1.0585
MCF 10A Linsitinib
0.37
uM
LJP5
 72
hr
 513 4475 10401 0.4303 0.4007