LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A Mitoxantrone
0.37
uM
LJP5
 72
hr
 513 555 10401 0.0534 0.0043
MCF 10A Mitoxantrone
0.37
uM
LJP6
 72
hr
 513 552 10401 0.0531 0.0039
MCF 10A MK2206
0.37
uM
LJP6
 72
hr
 513 2813 10401 0.2705 0.2326
MCF 10A Neratinib
0.37
uM
LJP5
 72
hr
 513 778 10401 0.0748 0.0268
MCF 10A Nilotinib
0.37
uM
LJP5
 72
hr
 513 9986 10401 0.9601 0.9581
MCF 10A Nintedanib
0.37
uM
LJP6
 72
hr
 513 10390 10401 0.9990 0.9989
MCF 10A NU7441
0.37
uM
LJP5
 72
hr
 513 10085 10401 0.9697 0.9681
MCF 10A Dactolisib
0.37
uM
LJP5
 72
hr
 513 943 10401 0.0907 0.0435
MCF 10A NVP-TAE684
0.37
uM
LJP6
 72
hr
 513 2944 10401 0.2831 0.2459
MCF 10A Palbociclib
0.37
uM
LJP6
 72
hr
 513 4868 10401 0.4680 0.4404
MCF 10A PD0325901
0.37
uM
LJP5
 72
hr
 513 801 10401 0.0770 0.0291
MCF 10A PD0325901
0.37
uM
LJP6
 72
hr
 513 675 10401 0.0649 0.0163
MCF 10A PD173074
0.37
uM
LJP6
 72
hr
 513 10522 10401 1.0117 1.0123
MCF 10A PD184352
0.37
uM
LJP5
 72
hr
 513 2140 10401 0.2058 0.1645
MCF 10A Pelitinib
0.37
uM
LJP5
 72
hr
 513 724 10401 0.0697 0.0214
MCF 10A PF431396
0.37
uM
LJP5
 72
hr
 513 1183 10401 0.1138 0.0678
MCF 10A PF477736
0.37
uM
LJP5
 72
hr
 513 7576 10401 0.7285 0.7144
MCF 10A PF562271
0.37
uM
LJP6
 72
hr
 513 4631 10401 0.4453 0.4165
MCF 10A PHA-665752
0.37
uM
LJP5
 72
hr
 513 9740 10401 0.9365 0.9332
MCF 10A PHA-793887
0.37
uM
LJP6
 72
hr
 513 745 10401 0.0717 0.0235
MCF 10A PI103
0.37
uM
LJP6
 72
hr
 513 1481 10401 0.1424 0.0979
MCF 10A PLX-4720
0.37
uM
LJP5
 72
hr
 513 11131 10401 1.0702 1.0738
MCF 10A QL-X-138
0.37
uM
LJP6
 72
hr
 513 5540 10401 0.5327 0.5084
MCF 10A QL-XII-47
0.37
uM
LJP6
 72
hr
 513 5964 10401 0.5735 0.5513
MCF 10A Radicicol
0.37
uM
LJP5
 72
hr
 513 794 10401 0.0763 0.0284