LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A Radicicol
0.37
uM
LJP6
 72
hr
 513 841 10401 0.0809 0.0331
MCF 10A Seliciclib
0.37
uM
LJP5
 72
hr
 513 9694 10401 0.9320 0.9285
MCF 10A Ruxolitinib
0.37
uM
LJP5
 72
hr
 513 9609 10401 0.9239 0.9199
MCF 10A XL147
0.37
uM
LJP5
 72
hr
 513 9954 10401 0.9570 0.9548
MCF 10A Saracatinib
0.37
uM
LJP6
 72
hr
 513 7574 10401 0.7282 0.7141
MCF 10A Selumetinib
0.37
uM
LJP6
 72
hr
 513 1629 10401 0.1567 0.1129
MCF 10A Sirolimus
0.37
uM
LJP6
 72
hr
 513 10033 10401 0.9647 0.9628
MCF 10A Sorafenib
0.37
uM
LJP6
 72
hr
 513 10330 10401 0.9932 0.9928
MCF 10A SU11274
0.37
uM
LJP5
 72
hr
 513 9431 10401 0.9067 0.9019
MCF 10A Fedratinib
0.37
uM
LJP5
 72
hr
 513 9475 10401 0.9110 0.9064
MCF 10A TGX221
0.37
uM
LJP5
 72
hr
 513 9094 10401 0.8743 0.8678
MCF 10A Torin1
0.37
uM
LJP6
 72
hr
 513 1114 10401 0.1071 0.0608
MCF 10A Torin2
0.37
uM
LJP5
 72
hr
 513 472 10401 0.0454 -0.0042
MCF 10A Tozasertib
0.37
uM
LJP5
 72
hr
 513 1079 10401 0.1038 0.0572
MCF 10A Trametinib
0.37
uM
LJP5
 72
hr
 513 737 10401 0.0709 0.0226
MCF 10A TWS119
0.37
uM
LJP5
 72
hr
 513 10898 10401 1.0478 1.0502
MCF 10A Vemurafenib
0.37
uM
LJP5
 72
hr
 513 9959 10401 0.9576 0.9554
MCF 10A Withaferin A
0.37
uM
LJP5
 72
hr
 513 7214 10401 0.6936 0.6777
MCF 10A Withaferin A
0.37
uM
LJP6
 72
hr
 513 6298 10401 0.6055 0.5850
MCF 10A WYE-125132
0.37
uM
LJP6
 72
hr
 513 1303 10401 0.1253 0.0799
MCF 10A WZ3105
0.37
uM
LJP5
 72
hr
 513 678 10401 0.0652 0.0167
MCF 10A XMD11-50
0.37
uM
LJP6
 72
hr
 513 7006 10401 0.6736 0.6567
MCF 10A Y39983
0.37
uM
LJP6
 72
hr
 513 7611 10401 0.7318 0.7178
MCF 10A YM 201636
0.37
uM
LJP5
 72
hr
 513 8987 10401 0.8641 0.8571
MCF 10A ZSTK474
0.37
uM
LJP6
 72
hr
 513 3122 10401 0.3002 0.2638