Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Docetaxel | BT-549 | -5.0000 | 0.9751 | -8.5540 | -8.3753 | -8.5191 | 1.7370 | 0.2542 | 0.2542 | 4.8575 |
| Docetaxel | CAMA-1 | -5.0000 | 0.9704 | -8.2760 | -8.0939 | -8.3245 | 3.9980 | 0.4062 | 0.4062 | 5.9096 |
| Docetaxel | HCC1143 | -5.0000 | 0.9068 | -7.9820 | -7.6856 | -8.0792 | 2.5470 | 0.3678 | 0.3679 | 6.0751 |
| Docetaxel | HCC1395 | -5.0000 | 0.8432 | -8.1310 | -7.8841 | -8.3044 | 2.0065 | 0.3383 | 0.3383 | 5.8332 |
| Docetaxel | HCC1419 | -5.0000 | 0.7471 | -7.7670 | -5.0000 | -7.8886 | 1.6530 | 0.7057 | 0.7057 | 8.4471 |
| Docetaxel | HCC1428 | -5.0000 | 0.8405 | -8.0940 | -5.0000 | -6.4032 | 1.0855 | 0.7934 | 0.7935 | 8.4257 |
| Docetaxel | HCC1569 | -5.0000 | 0.8391 | -8.5935 | -5.0000 | -8.0854 | 1.4385 | 0.5932 | 0.5932 | 6.7816 |
| Docetaxel | HCC1806 | -5.0000 | 0.9937 | -8.5945 | -8.5659 | -8.6584 | 2.1230 | 0.0853 | 0.0853 | 3.8338 |
| Docetaxel | HCC1937 | -5.0000 | 0.9371 | -8.2330 | -5.0000 | -8.2189 | 3.9980 | 0.6654 | 0.6654 | 7.3654 |
| Docetaxel | HCC1954 | -5.0000 | 0.9115 | -8.6430 | -8.5724 | -8.8092 | 1.2620 | 0.0624 | 0.0624 | 3.8091 |
| Docetaxel | HCC202 | -5.0000 | 0.8692 | -7.9460 | -5.8641 | -8.3190 | 0.8815 | 0.4927 | 0.4940 | 6.5284 |
| Docetaxel | HCC38 | -5.0000 | 0.9818 | -8.6120 | -8.4709 | -8.7384 | 1.9535 | 0.2238 | 0.2238 | 4.5902 |
| Docetaxel | HCC70 | -5.0000 | 0.9713 | -8.1680 | -7.8487 | -8.5185 | 1.5350 | 0.2799 | 0.2799 | 5.4623 |
| Docetaxel | Hs 578T | -5.0000 | 0.9693 | -8.6405 | -8.5044 | -8.8125 | 1.4793 | 0.1759 | 0.1761 | 4.2545 |
| Docetaxel | MB 157 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Docetaxel | MDA-MB-134-VI | -5.0000 | 0.9854 | -8.1760 | -7.8585 | -8.2672 | 1.6740 | 0.3530 | 0.3530 | 7.8615 |
| Docetaxel | MDA-MB-157 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Docetaxel | MDA-MB-175-VII | -5.0000 | 0.8165 | -8.0975 | -5.0000 | -7.8058 | 2.7620 | 0.7630 | 0.7630 | 7.7847 |
| Docetaxel | MDA-MB-361 | -5.0000 | 0.9451 | -8.1250 | -6.2289 | -8.0978 | 1.9955 | 0.5056 | 0.5056 | 6.5259 |
| Docetaxel | MDA-MB-436 | -5.0000 | 0.8183 | -7.7540 | -7.4465 | -7.7477 | 3.9940 | 0.4703 | 0.4703 | 6.9177 |
| Docetaxel | MDA-MB-453 | -5.0000 | 0.9073 | -8.1335 | -7.7961 | -8.3189 | 1.9845 | 0.3775 | 0.3775 | 6.1263 |
| Docetaxel | MDA-MB-468 | -5.0000 | 0.9839 | -8.5860 | -8.5206 | -8.7081 | 1.8710 | 0.0837 | 0.0837 | 3.8228 |
| Docetaxel | T47D | -5.0000 | 0.9188 | -8.4910 | -5.0000 | -8.5398 | 3.9735 | 0.5283 | 0.5283 | 6.5864 |
| Docetaxel | UACC-812 | -5.0000 | 0.8381 | -8.3850 | -5.0000 | -8.3827 | 3.1055 | 0.6724 | 0.6724 | 7.3992 |
| Docetaxel | UACC-893 | -5.0000 | 0.8516 | -7.7670 | -7.4530 | -7.8897 | 3.9970 | 0.4722 | 0.4722 | 7.5379 |