Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Carboplatin | MDA-MB-134-VI | -2.8697 | 0.8463 | -3.3983 | -3.3930 | -3.6484 | 3.5530 | 0.0229 | 0.0509 | 8.1638 |
| Carboplatin | MDA-MB-157 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Carboplatin | MDA-MB-175-VII | -2.8697 | 0.9711 | -3.9657 | -3.9613 | -4.4163 | 1.5290 | 0.0080 | 0.0293 | 7.0121 |
| Carboplatin | MDA-MB-361 | -2.8697 | 0.9838 | -3.8066 | -3.7269 | -4.3279 | 1.1910 | 0.0983 | 0.1998 | 7.3948 |
| Carboplatin | MDA-MB-436 | -2.8697 | 0.8798 | -3.8884 | -3.8436 | -4.2922 | 1.2575 | 0.0603 | 0.1081 | 7.3592 |
| Carboplatin | MDA-MB-453 | -2.8697 | 0.8866 | -4.0877 | -4.0304 | -4.2419 | 1.7980 | 0.0782 | 0.0892 | 7.5353 |
| Carboplatin | MDA-MB-468 | -2.8697 | 0.8220 | -4.1407 | -4.1411 | -4.2978 | 2.2170 | 0.0000 | 0.0028 | 6.7013 |
| Carboplatin | T47D | -2.8697 | 0.9629 | -3.3224 | -3.3224 | -4.0221 | 0.8599 | 0.0000 | 0.2927 | 7.7802 |
| Carboplatin | UACC-812 | -2.8697 | 0.9453 | -4.2547 | -4.2331 | -4.6378 | 2.2680 | 0.0566 | 0.0594 | 7.0657 |
| Carboplatin | UACC-893 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Carboplatin | ZR-75-1 | -2.8697 | 0.9764 | -3.7268 | -3.7267 | -4.1025 | 1.2220 | 0.0000 | 0.0805 | 7.3015 |
| Carboplatin | 184B5 | -2.8697 | 0.9700 | -4.9237 | -4.9237 | -5.2930 | 1.0740 | 0.0000 | 0.0062 | 5.6519 |
| Carboplatin | HCC1187 | -2.8697 | 0.9427 | -4.3727 | -4.3686 | -4.5464 | 3.5025 | 0.0172 | 0.0172 | 6.7142 |
| Carboplatin | MCF 10A | -2.8697 | 0.9617 | -4.0847 | -4.0851 | -4.2144 | 1.3600 | 0.0000 | 0.0203 | 6.8904 |
| Carboplatin | MCF 10F | -2.8697 | 0.9901 | -4.3007 | -4.3011 | -4.4202 | 1.4680 | 0.0000 | 0.0079 | 6.4409 |
| Carboplatin | SUM1315MO2 | -2.8697 | 0.9835 | -4.1577 | -4.1576 | -4.4918 | 1.9670 | 0.0000 | 0.0031 | 6.7231 |
| Carboplatin | SUM149PT | -2.8697 | 0.9789 | -4.7477 | -4.7478 | -4.8660 | 1.3295 | 0.0000 | 0.0032 | 5.7224 |
| Carboplatin | SUM159PT | -2.8697 | 0.9847 | -4.5177 | -4.5141 | -4.5431 | 2.5320 | 0.0143 | 0.0143 | 6.2945 |
| Carboplatin | SUM185PE | -2.8697 | 0.9634 | -3.5495 | -3.5495 | -3.9211 | 1.6660 | 0.0000 | 0.0703 | 7.6061 |
| Carboplatin | SUM225CWN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Carboplatin | SUM229PE | -2.8697 | 0.8274 | -4.2287 | -4.1552 | -4.2629 | 3.9940 | 0.2461 | 0.2461 | 8.2253 |
| Carboplatin | SUM52PE | -2.8697 | 0.9543 | -4.3877 | -4.3824 | -4.7244 | 1.0595 | 0.0064 | 0.0305 | 6.4928 |
| Carboplatin | 184A1 | -2.8697 | 0.9549 | -4.7112 | -4.6379 | -4.9293 | 2.5095 | 0.1727 | 0.1727 | 6.2179 |
| Carboplatin | MCF12A | -2.8697 | 0.9763 | -3.9262 | -3.9261 | -4.0632 | 1.4725 | 0.0000 | 0.0423 | 6.9985 |
| Carboplatin | MX1 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |