Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| XRP44X | BT-20 | -3.8761 | 0.8096 | -5.4871 | -3.8761 | -5.3396 | 2.0185 | 0.5449 | 0.5451 | 7.5268 |
| XRP44X | BT-474 | -3.8761 | 0.7217 | -5.4566 | -3.8761 | -5.6052 | 2.5750 | 0.5740 | 0.5824 | 8.0983 |
| XRP44X | BT-483 | -3.8761 | 0.9123 | -4.2741 | -4.2741 | -6.5942 | 0.3963 | 0.0000 | 0.4102 | 7.6105 |
| XRP44X | BT-549 | -3.8761 | 0.7711 | -5.9581 | -5.7791 | -5.8646 | 1.9270 | 0.2745 | 0.2746 | 6.0076 |
| XRP44X | CAMA-1 | -3.8761 | 0.9426 | -6.1091 | -5.9382 | -6.1744 | 3.4615 | 0.3672 | 0.3672 | 6.4770 |
| XRP44X | HCC1143 | -3.8761 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 6.9319 |
| XRP44X | HCC1395 | -3.8761 | 0.8472 | -5.9991 | -5.7639 | -6.0567 | 3.9950 | 0.4424 | 0.4424 | 7.2165 |
| XRP44X | HCC1419 | -3.8761 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 8.3133 |
| XRP44X | HCC1428 | -3.8761 | 0.8842 | -6.0151 | -3.8761 | -5.8419 | 3.6330 | 0.7028 | 0.7028 | 7.6465 |
| XRP44X | HCC1569 | -3.8761 | 0.7363 | -5.7191 | -3.8761 | -5.3606 | 1.1140 | 0.5651 | 0.5689 | 8.1058 |
| XRP44X | HCC1806 | -3.8761 | 0.9698 | -5.9361 | -5.8750 | -5.9745 | 2.3990 | 0.1426 | 0.1426 | 6.2045 |
| XRP44X | HCC1937 | -3.8761 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 8.2896 |
| XRP44X | HCC1954 | -3.8761 | 0.9458 | -6.3851 | -6.3213 | -6.4332 | 2.4930 | 0.1535 | 0.1535 | 5.1400 |
| XRP44X | HCC202 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| XRP44X | HCC38 | -3.8761 | 0.9360 | -5.7926 | -5.6274 | -5.8223 | 1.6370 | 0.2263 | 0.2270 | 6.4599 |
| XRP44X | HCC70 | -3.8761 | 0.9248 | -5.9571 | -5.8481 | -5.9972 | 3.9910 | 0.3156 | 0.3156 | 6.8192 |
| XRP44X | Hs 578T | -3.8761 | 0.9861 | -6.0671 | -5.9899 | -6.0468 | 3.9990 | 0.2542 | 0.2542 | 6.3019 |
| XRP44X | MB 157 | -3.8761 | 0.9962 | -5.9311 | -5.7887 | -5.9350 | 1.9780 | 0.2386 | 0.2387 | 6.3513 |
| XRP44X | MDA-MB-134-VI | -3.8761 | 0.9645 | -5.9221 | -5.5042 | -6.0070 | 1.7895 | 0.4011 | 0.4013 | 7.0335 |
| XRP44X | MDA-MB-157 | -3.8761 | 0.9867 | -5.8791 | -5.8080 | -5.9381 | 3.9990 | 0.2405 | 0.2405 | 6.4779 |
| XRP44X | MDA-MB-175-VII | -3.8761 | 0.9064 | -5.8031 | -3.8761 | -5.7271 | 2.9455 | 0.7344 | 0.7344 | 8.0381 |
| XRP44X | MDA-MB-361 | -3.8761 | 0.8343 | -5.9361 | -3.8761 | -6.0304 | 3.9860 | 0.5121 | 0.5121 | 7.6808 |
| XRP44X | MDA-MB-436 | -3.8761 | 0.7416 | -5.9051 | -3.8761 | -5.8819 | 3.9970 | 0.5494 | 0.5494 | 7.7086 |
| XRP44X | MDA-MB-453 | -3.8761 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 6.8282 |
| XRP44X | MDA-MB-468 | -3.8761 | 0.8812 | -5.9701 | -5.8933 | -5.9503 | 3.9990 | 0.2529 | 0.2529 | 6.0945 |