Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| XRP44X | T47D | -3.8761 | 0.9505 | -5.4821 | -5.2276 | -5.4598 | 1.8560 | 0.3314 | 0.3321 | 6.9916 |
| XRP44X | UACC-812 | -3.8761 | 0.8936 | -6.2051 | -5.1853 | -6.2271 | 1.7560 | 0.4919 | 0.4919 | 6.9011 |
| XRP44X | UACC-893 | -3.8761 | 0.9262 | -5.9171 | -5.4519 | -6.0317 | 2.9140 | 0.4780 | 0.4780 | 7.1128 |
| XRP44X | ZR-75-1 | -3.8761 | 0.8068 | -5.9791 | -3.8761 | -5.9305 | 3.9040 | 0.6037 | 0.6037 | 7.1542 |
| XRP44X | 184B5 | -3.8761 | 0.9686 | -6.7791 | -5.5007 | -6.5750 | 0.7813 | 0.4499 | 0.4529 | 6.3885 |
| XRP44X | HCC1187 | -3.8761 | 0.9808 | -6.0121 | -5.9824 | -6.1024 | 3.6405 | 0.1103 | 0.1103 | 5.8199 |
| XRP44X | MCF 10A | -3.8761 | 0.9819 | -6.4591 | -6.4245 | -6.4557 | 3.9960 | 0.1369 | 0.1369 | 5.4340 |
| XRP44X | MCF 10F | -3.8761 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 8.6891 |
| XRP44X | SUM1315MO2 | -3.8761 | 0.9876 | -6.1251 | -6.0665 | -6.3597 | 2.2970 | 0.1324 | 0.1324 | 6.5590 |
| XRP44X | SUM149PT | -3.8761 | 0.8856 | -5.9871 | -5.8456 | -5.9381 | 3.5925 | 0.3393 | 0.3393 | 6.6806 |
| XRP44X | SUM159PT | -3.8761 | 0.9201 | -6.2976 | -6.2735 | -6.2992 | 2.5635 | 0.0733 | 0.0733 | 5.1111 |
| XRP44X | SUM185PE | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| XRP44X | SUM225CWN | -3.8761 | 0.8463 | -5.7491 | -3.8761 | -5.7022 | 2.9390 | 0.5317 | 0.5317 | 7.7320 |
| XRP44X | SUM229PE | -3.8761 | 0.9331 | -6.5831 | -6.4544 | -6.5363 | 4.0000 | 0.3473 | 0.3473 | 5.9861 |
| XRP44X | SUM52PE | -3.8761 | 0.9367 | -6.1976 | -6.0840 | -6.2513 | 2.9750 | 0.2407 | 0.2407 | 6.1185 |
| XRP44X | 184A1 | -3.8761 | 0.9432 | -6.8881 | -3.8761 | -6.4727 | 1.3400 | 0.6235 | 0.6235 | 7.2068 |
| XRP44X | MCF12A | -3.8761 | 0.9763 | -6.6931 | -6.5021 | -6.6819 | 2.0905 | 0.2683 | 0.2684 | 5.6601 |
| XRP44X | MX1 | -3.8761 | 0.9777 | -6.0991 | -6.0602 | -6.2806 | 3.3205 | 0.1321 | 0.1321 | 5.7706 |
| XRP44X | T47DKBLUC | -3.8761 | 0.9094 | -5.7021 | -5.4025 | -5.7059 | 3.9940 | 0.4681 | 0.4681 | 7.1405 |
| XRP44X | 600MPE | -3.8761 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 8.2243 |
| XRP44X | HCC2185 | -3.8761 | 0.8594 | -6.1671 | -5.9741 | -6.2836 | 3.9985 | 0.3949 | 0.3949 | 6.7505 |
| XRP44X | HCC3153 | -3.8761 | 0.9371 | -5.6386 | -5.4496 | -5.7524 | 2.4773 | 0.2864 | 0.2918 | 6.9214 |
| XRP44X | LY2 | -3.8761 | 0.9286 | -6.1841 | -6.0850 | -6.2519 | 4.0000 | 0.2990 | 0.2990 | 6.4083 |
| XRP44X | ZR75B | -3.8761 | 0.8594 | -6.0381 | -5.4220 | -5.9202 | 1.7480 | 0.4581 | 0.4582 | 6.8995 |
| Baicalein | MCF7 | -3.7773 | 0.8402 | -3.9008 | -3.9362 | -3.9849 | 3.9870 | 0.0193 | 0.3800 | 8.3537 |