Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Oxamflatin | BT-483 | -4.1759 | 0.9477 | -5.2746 | -5.2747 | -6.3576 | 0.8319 | 0.0000 | 0.1110 | 6.5742 |
| Oxamflatin | BT-549 | -4.1759 | 0.9578 | -5.9179 | -5.9185 | -6.0017 | 1.3390 | 0.0000 | 0.0046 | 6.0646 |
| Oxamflatin | CAMA-1 | -4.1759 | 0.9615 | -5.8954 | -5.8751 | -6.1584 | 2.1740 | 0.0453 | 0.0455 | 5.9953 |
| Oxamflatin | HCC1143 | -4.1759 | 0.9316 | -6.0689 | -6.0690 | -6.3709 | 0.8181 | 0.0000 | 0.0275 | 5.5301 |
| Oxamflatin | HCC1395 | -4.1759 | 0.9435 | -5.3764 | -5.3755 | -5.6755 | 1.6340 | 0.0010 | 0.0119 | 6.6696 |
| Oxamflatin | HCC1419 | -4.1759 | 0.8918 | -5.1799 | -5.1797 | -5.9343 | 1.0710 | 0.0000 | 0.0776 | 6.6278 |
| Oxamflatin | HCC1428 | -4.1759 | 0.9747 | -6.1564 | -6.1494 | -6.3189 | 3.2630 | 0.0271 | 0.0271 | 5.5477 |
| Oxamflatin | HCC1569 | -4.1759 | 0.9855 | -5.6739 | -5.6636 | -5.8921 | 2.0115 | 0.0320 | 0.0395 | 6.3603 |
| Oxamflatin | HCC1806 | -4.1759 | 0.9896 | -5.9819 | -5.9817 | -6.1950 | 1.0200 | 0.0000 | 0.0142 | 5.8477 |
| Oxamflatin | HCC1937 | -4.1759 | 0.9642 | -5.5679 | -5.5680 | -5.8349 | 1.4160 | 0.0000 | 0.0106 | 6.4585 |
| Oxamflatin | HCC1954 | -4.1759 | 0.9721 | -5.5289 | -5.5292 | -5.8578 | 0.8759 | 0.0000 | 0.0613 | 6.3145 |
| Oxamflatin | HCC202 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Oxamflatin | HCC38 | -4.1759 | 0.9761 | -6.6779 | -6.6763 | -6.8320 | 1.3210 | 0.0030 | 0.0035 | 4.7352 |
| Oxamflatin | HCC70 | -4.1759 | 0.9752 | -6.0734 | -6.0738 | -6.3833 | 1.2700 | 0.0000 | 0.0044 | 5.5747 |
| Oxamflatin | Hs 578T | -4.1759 | 0.9924 | -5.7969 | -5.7869 | -5.8992 | 1.5240 | 0.0171 | 0.0204 | 6.2041 |
| Oxamflatin | MB 157 | -4.1759 | 0.9933 | -6.0469 | -6.0431 | -6.2040 | 1.1690 | 0.0054 | 0.0118 | 5.8284 |
| Oxamflatin | MDA-MB-134-VI | -4.1759 | 0.9687 | -5.5894 | -5.5895 | -6.1794 | 0.9469 | 0.0000 | 0.0454 | 6.4246 |
| Oxamflatin | MDA-MB-157 | -4.1759 | 0.9752 | -5.8159 | -5.8159 | -6.1392 | 1.0510 | 0.0000 | 0.0185 | 6.1566 |
| Oxamflatin | MDA-MB-175-VII | -4.1759 | 0.9402 | -4.8713 | -4.8714 | -5.6373 | 1.3020 | 0.0000 | 0.1106 | 7.1048 |
| Oxamflatin | MDA-MB-361 | -4.1759 | 0.9780 | -5.7989 | -5.7974 | -6.1307 | 1.7805 | 0.0036 | 0.0057 | 6.1787 |
| Oxamflatin | MDA-MB-436 | -4.1759 | 0.9441 | -4.9770 | -4.6942 | -5.3119 | 0.8499 | 0.2125 | 0.3484 | 7.8309 |
| Oxamflatin | MDA-MB-453 | -4.1759 | 0.9644 | -6.2329 | -6.2329 | -6.5972 | 1.2140 | 0.0000 | 0.0032 | 5.2727 |
| Oxamflatin | MDA-MB-468 | -4.1759 | 0.9400 | -5.4679 | -5.4549 | -5.5414 | 2.4450 | 0.0342 | 0.0349 | 7.0509 |
| Oxamflatin | T47D | -4.1759 | 0.9807 | -5.9139 | -5.9139 | -6.1067 | 1.4120 | 0.0000 | 0.0035 | 5.9155 |
| Oxamflatin | UACC-812 | -4.1759 | 0.9071 | -5.2654 | -5.2656 | -5.8217 | 1.0263 | 0.0000 | 0.0782 | 6.6977 |