Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Oxaliplatin | HCC1187 | -3.2013 | 0.9626 | -5.4688 | -5.4567 | -5.7340 | 2.6570 | 0.0329 | 0.0333 | 5.6723 |
| Oxaliplatin | MCF 10A | -3.2013 | 0.9357 | -5.1263 | -5.1265 | -5.4388 | 0.6126 | 0.0000 | 0.0687 | 5.8246 |
| Oxaliplatin | MCF 10F | -3.2013 | 0.9550 | -5.1153 | -5.1157 | -5.3478 | 0.5858 | 0.0000 | 0.0703 | 5.7552 |
| Oxaliplatin | SUM1315MO2 | -3.2013 | 0.9567 | -4.4548 | -4.4537 | -4.8160 | 1.9195 | 0.0034 | 0.0110 | 6.8557 |
| Oxaliplatin | SUM149PT | -3.2013 | 0.9702 | -5.6473 | -5.6477 | -5.8640 | 0.6884 | 0.0000 | 0.0210 | 5.0266 |
| Oxaliplatin | SUM159PT | -3.2013 | 0.9842 | -5.5843 | -5.5638 | -5.6109 | 1.1880 | 0.0302 | 0.0308 | 5.1424 |
| Oxaliplatin | SUM185PE | -3.2013 | 0.9630 | -4.2608 | -4.2538 | -4.4424 | 2.9665 | 0.0256 | 0.0271 | 6.9847 |
| Oxaliplatin | SUM225CWN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Oxaliplatin | SUM229PE | -3.2013 | 0.9120 | -5.4753 | -5.2234 | -5.7059 | 0.8201 | 0.1892 | 0.2001 | 6.3509 |
| Oxaliplatin | SUM52PE | -3.2013 | 0.9665 | -4.9958 | -4.9960 | -5.4386 | 0.8243 | 0.0000 | 0.0330 | 6.0562 |
| Oxaliplatin | 184A1 | -3.2013 | 0.9677 | -5.1663 | -5.1606 | -5.8995 | 0.9161 | 0.0074 | 0.0267 | 5.6724 |
| Oxaliplatin | MCF12A | -3.2013 | 0.9322 | -5.4328 | -5.4326 | -5.7545 | 0.5884 | 0.0000 | 0.0502 | 5.3792 |
| Oxaliplatin | MX1 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Oxaliplatin | T47DKBLUC | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Oxaliplatin | 600MPE | -3.2013 | 0.9767 | -4.3656 | -4.2834 | -4.8172 | 1.0950 | 0.0824 | 0.1320 | 7.0948 |
| Oxaliplatin | HCC2185 | -3.2013 | 0.9879 | -4.6893 | -4.6773 | -5.4959 | 1.1250 | 0.0000 | 0.0430 | 6.4825 |
| Oxaliplatin | HCC3153 | -3.2013 | 0.9547 | -4.6838 | -4.6842 | -5.2037 | 0.7876 | 0.0000 | 0.0642 | 6.3091 |
| Oxaliplatin | LY2 | -3.2013 | 0.9645 | -4.8878 | -4.8875 | -5.4591 | 0.6638 | 0.0000 | 0.0763 | 6.0549 |
| Oxaliplatin | ZR75B | -3.2013 | 0.9141 | -4.7143 | -4.7144 | -5.5795 | 0.5251 | 0.0000 | 0.1383 | 6.3525 |
| Oxamflatin | MCF7 | -4.1759 | 0.9556 | -5.5379 | -5.4857 | -5.7907 | 1.2140 | 0.0678 | 0.0880 | 6.5388 |
| Oxamflatin | SK-BR-3 | -4.1759 | 0.9763 | -5.6919 | -5.6915 | -5.9755 | 1.2620 | 0.0000 | 0.0121 | 6.1565 |
| Oxamflatin | MDA-MB-231 | -4.1759 | 0.8193 | -5.5509 | -5.5427 | -5.5779 | 3.9930 | 0.0364 | 0.0364 | 7.6753 |
| Oxamflatin | AU565 | -4.1759 | 0.9575 | -6.0559 | -6.0530 | -6.2067 | 2.0570 | 0.0071 | 0.0072 | 5.7252 |
| Oxamflatin | BT-20 | -4.1759 | 0.9586 | -5.0761 | -5.0762 | -5.4347 | 1.1875 | 0.0000 | 0.0786 | 7.3141 |
| Oxamflatin | BT-474 | -4.1759 | 0.9370 | -5.8619 | -5.8611 | -6.5901 | 0.9464 | 0.0000 | 0.0395 | 5.8729 |