Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-X-138 | 3 | 72 | 3.1623 | 3217.0 | 6533.6 | 1943.1 | 0.5 | 0.334 | 0.492 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 3.1623 | 3113.0 | 6533.6 | 1943.1 | 0.5 | 0.309 | 0.476 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 10.0 | 1192.0 | 6533.6 | 1943.1 | 1.0 | -0.244 | 0.182 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 10.0 | 1242.0 | 6533.6 | 1943.1 | 1.0 | -0.226 | 0.190 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 10.0 | 1213.0 | 6533.6 | 1943.1 | 1.0 | -0.236 | 0.186 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 10.0 | 1178.0 | 6533.6 | 1943.1 | 1.0 | -0.249 | 0.180 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.001 | 7751.0 | 7580.8 | 2503.8 | -3.0 | 1.030 | 1.020 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.001 | 7224.0 | 7580.8 | 2503.8 | -3.0 | 0.941 | 0.953 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.001 | 7080.0 | 7580.8 | 2503.8 | -3.0 | 0.916 | 0.934 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.001 | 7982.0 | 7580.8 | 2503.8 | -3.0 | 1.070 | 1.050 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.0032 | 7623.0 | 7580.8 | 2503.8 | -2.49 | 1.010 | 1.010 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.0032 | 7075.0 | 7580.8 | 2503.8 | -2.49 | 0.915 | 0.933 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.0032 | 7214.0 | 7580.8 | 2503.8 | -2.49 | 0.939 | 0.952 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.0032 | 7272.0 | 7580.8 | 2503.8 | -2.49 | 0.949 | 0.959 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.01 | 7972.0 | 7580.8 | 2503.8 | -2.0 | 1.060 | 1.050 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.01 | 7602.0 | 7580.8 | 2503.8 | -2.0 | 1.000 | 1.000 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.01 | 7243.0 | 7580.8 | 2503.8 | -2.0 | 0.944 | 0.955 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.01 | 8057.0 | 7580.8 | 2503.8 | -2.0 | 1.080 | 1.060 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.0316 | 6742.0 | 7580.8 | 2503.8 | -1.5 | 0.859 | 0.889 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.0316 | 6667.0 | 7580.8 | 2503.8 | -1.5 | 0.846 | 0.879 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.0316 | 7509.0 | 7580.8 | 2503.8 | -1.5 | 0.988 | 0.991 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.0316 | 6973.0 | 7580.8 | 2503.8 | -1.5 | 0.898 | 0.920 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.1 | 7255.0 | 7580.8 | 2503.8 | -1.0 | 0.946 | 0.957 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.1 | 7351.0 | 7580.8 | 2503.8 | -1.0 | 0.962 | 0.970 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.1 | 7947.0 | 7580.8 | 2503.8 | -1.0 | 1.060 | 1.050 | 1.598 | HCC70 QL-XII-108 0 1 |