Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-VI-86 | 2 | 72 | 10.0 | 385.0 | 7167.9 | 2409.0 | 1.0 | -0.688 | 0.054 | 1.573 | HCC70 QL-VI-86 0 2 |
| HCC70 | QL-VI-86 | 2 | 72 | 10.0 | 337.0 | 7167.9 | 2409.0 | 1.0 | -0.714 | 0.047 | 1.573 | HCC70 QL-VI-86 0 2 |
| HCC70 | QL-VI-86 | 2 | 72 | 10.0 | 385.0 | 7167.9 | 2409.0 | 1.0 | -0.688 | 0.054 | 1.573 | HCC70 QL-VI-86 0 2 |
| HCC70 | QL-VI-86 | 2 | 72 | 10.0 | 383.0 | 7167.9 | 2409.0 | 1.0 | -0.689 | 0.053 | 1.573 | HCC70 QL-VI-86 0 2 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.001 | 5841.0 | 6533.6 | 1943.1 | -3.0 | 0.876 | 0.894 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.001 | 5929.0 | 6533.6 | 1943.1 | -3.0 | 0.892 | 0.907 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.001 | 6456.0 | 6533.6 | 1943.1 | -3.0 | 0.986 | 0.988 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.001 | 6440.0 | 6533.6 | 1943.1 | -3.0 | 0.984 | 0.986 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.0032 | 5851.0 | 6533.6 | 1943.1 | -2.49 | 0.878 | 0.896 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.0032 | 6162.0 | 6533.6 | 1943.1 | -2.49 | 0.934 | 0.943 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.0032 | 6119.0 | 6533.6 | 1943.1 | -2.49 | 0.926 | 0.937 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.0032 | 6571.0 | 6533.6 | 1943.1 | -2.49 | 1.010 | 1.010 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.01 | 6570.0 | 6533.6 | 1943.1 | -2.0 | 1.010 | 1.010 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.01 | 6230.0 | 6533.6 | 1943.1 | -2.0 | 0.946 | 0.954 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.01 | 6317.0 | 6533.6 | 1943.1 | -2.0 | 0.962 | 0.967 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.01 | 6389.0 | 6533.6 | 1943.1 | -2.0 | 0.975 | 0.978 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.0316 | 6145.0 | 6533.6 | 1943.1 | -1.5 | 0.931 | 0.941 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.0316 | 5614.0 | 6533.6 | 1943.1 | -1.5 | 0.834 | 0.859 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.0316 | 5269.0 | 6533.6 | 1943.1 | -1.5 | 0.769 | 0.806 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.0316 | 5688.0 | 6533.6 | 1943.1 | -1.5 | 0.848 | 0.871 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.1 | 4831.0 | 6533.6 | 1943.1 | -1.0 | 0.683 | 0.739 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.1 | 5356.0 | 6533.6 | 1943.1 | -1.0 | 0.785 | 0.820 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.1 | 4700.0 | 6533.6 | 1943.1 | -1.0 | 0.657 | 0.719 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.1 | 5444.0 | 6533.6 | 1943.1 | -1.0 | 0.802 | 0.833 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.3162 | 3809.0 | 6533.6 | 1943.1 | -0.5 | 0.469 | 0.583 | 1.750 | HCC70 QL-VI-86 0 3 |