Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | AZD8055 | 1 | 72 | 0.001 | 6645.0 | 7580.8 | 2503.8 | -3.0 | 0.842 | 0.877 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.001 | 6611.0 | 7580.8 | 2503.8 | -3.0 | 0.836 | 0.872 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.001 | 6827.0 | 7580.8 | 2503.8 | -3.0 | 0.873 | 0.901 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.001 | 7324.0 | 7580.8 | 2503.8 | -3.0 | 0.957 | 0.966 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.0032 | 6700.0 | 7580.8 | 2503.8 | -2.49 | 0.851 | 0.884 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.0032 | 6939.0 | 7580.8 | 2503.8 | -2.49 | 0.892 | 0.915 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.0032 | 6495.0 | 7580.8 | 2503.8 | -2.49 | 0.816 | 0.857 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.0032 | 7768.0 | 7580.8 | 2503.8 | -2.49 | 1.030 | 1.020 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.01 | 5715.0 | 7580.8 | 2503.8 | -2.0 | 0.676 | 0.754 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.01 | 5758.0 | 7580.8 | 2503.8 | -2.0 | 0.684 | 0.760 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.01 | 6315.0 | 7580.8 | 2503.8 | -2.0 | 0.784 | 0.833 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.01 | 5637.0 | 7580.8 | 2503.8 | -2.0 | 0.662 | 0.744 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.0316 | 4761.0 | 7580.8 | 2503.8 | -1.5 | 0.495 | 0.628 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.0316 | 5090.0 | 7580.8 | 2503.8 | -1.5 | 0.559 | 0.671 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.0316 | 5257.0 | 7580.8 | 2503.8 | -1.5 | 0.591 | 0.693 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.0316 | 4744.0 | 7580.8 | 2503.8 | -1.5 | 0.492 | 0.626 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.1 | 4013.0 | 7580.8 | 2503.8 | -1.0 | 0.343 | 0.529 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.1 | 4152.0 | 7580.8 | 2503.8 | -1.0 | 0.372 | 0.548 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.1 | 3940.0 | 7580.8 | 2503.8 | -1.0 | 0.328 | 0.520 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.1 | 3826.0 | 7580.8 | 2503.8 | -1.0 | 0.304 | 0.505 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.3162 | 3495.0 | 7580.8 | 2503.8 | -0.5 | 0.232 | 0.461 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.3162 | 3684.0 | 7580.8 | 2503.8 | -0.5 | 0.273 | 0.486 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.3162 | 3336.0 | 7580.8 | 2503.8 | -0.5 | 0.197 | 0.440 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.3162 | 3363.0 | 7580.8 | 2503.8 | -0.5 | 0.203 | 0.444 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 1.0 | 3289.0 | 7580.8 | 2503.8 | 0.0 | 0.186 | 0.434 | 1.598 | HCC70 AZD8055 0 1 |