Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-XII-108 | 1 | 72 | 0.1 | 8028.0 | 7580.8 | 2503.8 | -1.0 | 1.070 | 1.060 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.3162 | 6729.0 | 7580.8 | 2503.8 | -0.5 | 0.856 | 0.888 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.3162 | 6333.0 | 7580.8 | 2503.8 | -0.5 | 0.787 | 0.835 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.3162 | 6554.0 | 7580.8 | 2503.8 | -0.5 | 0.826 | 0.865 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.3162 | 6579.0 | 7580.8 | 2503.8 | -0.5 | 0.830 | 0.868 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 1.0 | 5231.0 | 7580.8 | 2503.8 | 0.0 | 0.586 | 0.690 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 1.0 | 5136.0 | 7580.8 | 2503.8 | 0.0 | 0.568 | 0.678 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 1.0 | 5316.0 | 7580.8 | 2503.8 | 0.0 | 0.602 | 0.701 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 1.0 | 5360.0 | 7580.8 | 2503.8 | 0.0 | 0.610 | 0.707 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 3.1623 | 4148.0 | 7580.8 | 2503.8 | 0.5 | 0.371 | 0.547 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 3.1623 | 3975.0 | 7580.8 | 2503.8 | 0.5 | 0.335 | 0.524 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 3.1623 | 3884.0 | 7580.8 | 2503.8 | 0.5 | 0.316 | 0.512 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 3.1623 | 4328.0 | 7580.8 | 2503.8 | 0.5 | 0.408 | 0.571 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 10.0 | 2735.0 | 7580.8 | 2503.8 | 1.0 | 0.057 | 0.361 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 10.0 | 2920.0 | 7580.8 | 2503.8 | 1.0 | 0.101 | 0.385 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 10.0 | 2777.0 | 7580.8 | 2503.8 | 1.0 | 0.067 | 0.366 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 10.0 | 3071.0 | 7580.8 | 2503.8 | 1.0 | 0.136 | 0.405 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 2 | 72 | 0.001 | 7074.0 | 7167.9 | 2409.0 | -3.0 | 0.983 | 0.987 | 1.573 | HCC70 QL-XII-108 0 2 |
| HCC70 | QL-XII-108 | 2 | 72 | 0.001 | 6635.0 | 7167.9 | 2409.0 | -3.0 | 0.904 | 0.926 | 1.573 | HCC70 QL-XII-108 0 2 |
| HCC70 | QL-XII-108 | 2 | 72 | 0.001 | 6580.0 | 7167.9 | 2409.0 | -3.0 | 0.894 | 0.918 | 1.573 | HCC70 QL-XII-108 0 2 |
| HCC70 | QL-XII-108 | 2 | 72 | 0.001 | 7399.0 | 7167.9 | 2409.0 | -3.0 | 1.040 | 1.030 | 1.573 | HCC70 QL-XII-108 0 2 |
| HCC70 | QL-XII-108 | 2 | 72 | 0.0032 | 7674.0 | 7167.9 | 2409.0 | -2.49 | 1.090 | 1.070 | 1.573 | HCC70 QL-XII-108 0 2 |
| HCC70 | QL-XII-108 | 2 | 72 | 0.0032 | 7010.0 | 7167.9 | 2409.0 | -2.49 | 0.972 | 0.978 | 1.573 | HCC70 QL-XII-108 0 2 |
| HCC70 | QL-XII-108 | 2 | 72 | 0.0032 | 6758.0 | 7167.9 | 2409.0 | -2.49 | 0.927 | 0.943 | 1.573 | HCC70 QL-XII-108 0 2 |
| HCC70 | QL-XII-108 | 2 | 72 | 0.0032 | 7290.0 | 7167.9 | 2409.0 | -2.49 | 1.020 | 1.020 | 1.573 | HCC70 QL-XII-108 0 2 |