Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-XII-61 | 2 | 72 | 0.1 | 7240.0 | 7167.9 | 2409.0 | -1.0 | 1.010 | 1.010 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 0.1 | 6542.0 | 7167.9 | 2409.0 | -1.0 | 0.887 | 0.913 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 0.1 | 7050.0 | 7167.9 | 2409.0 | -1.0 | 0.979 | 0.984 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 0.3162 | 7483.0 | 7167.9 | 2409.0 | -0.5 | 1.060 | 1.040 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 0.3162 | 7286.0 | 7167.9 | 2409.0 | -0.5 | 1.020 | 1.020 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 0.3162 | 7054.0 | 7167.9 | 2409.0 | -0.5 | 0.980 | 0.984 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 0.3162 | 7419.0 | 7167.9 | 2409.0 | -0.5 | 1.040 | 1.040 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 1.0 | 8286.0 | 7167.9 | 2409.0 | 0.0 | 1.190 | 1.160 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 1.0 | 7292.0 | 7167.9 | 2409.0 | 0.0 | 1.020 | 1.020 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 1.0 | 6916.0 | 7167.9 | 2409.0 | 0.0 | 0.955 | 0.965 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 1.0 | 7700.0 | 7167.9 | 2409.0 | 0.0 | 1.090 | 1.070 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 3.1623 | 6040.0 | 7167.9 | 2409.0 | 0.5 | 0.794 | 0.843 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 3.1623 | 6267.0 | 7167.9 | 2409.0 | 0.5 | 0.836 | 0.874 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 3.1623 | 6012.0 | 7167.9 | 2409.0 | 0.5 | 0.788 | 0.839 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 3.1623 | 6593.0 | 7167.9 | 2409.0 | 0.5 | 0.896 | 0.920 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 10.0 | 2628.0 | 7167.9 | 2409.0 | 1.0 | 0.057 | 0.367 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 10.0 | 3125.0 | 7167.9 | 2409.0 | 1.0 | 0.180 | 0.436 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 10.0 | 3538.0 | 7167.9 | 2409.0 | 1.0 | 0.277 | 0.494 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 10.0 | 3221.0 | 7167.9 | 2409.0 | 1.0 | 0.203 | 0.449 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.001 | 6297.0 | 6533.6 | 1943.1 | -3.0 | 0.958 | 0.964 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.001 | 5976.0 | 6533.6 | 1943.1 | -3.0 | 0.901 | 0.915 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.001 | 6843.0 | 6533.6 | 1943.1 | -3.0 | 1.050 | 1.050 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.001 | 6699.0 | 6533.6 | 1943.1 | -3.0 | 1.030 | 1.030 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.0032 | 6311.0 | 6533.6 | 1943.1 | -2.49 | 0.961 | 0.966 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.0032 | 6055.0 | 6533.6 | 1943.1 | -2.49 | 0.915 | 0.927 | 1.750 | HCC70 QL-XII-61 0 3 |