Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-XII-61 | 1 | 72 | 3.1623 | 6190.0 | 7580.8 | 2503.8 | 0.5 | 0.762 | 0.817 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 3.1623 | 6553.0 | 7580.8 | 2503.8 | 0.5 | 0.826 | 0.864 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 3.1623 | 6370.0 | 7580.8 | 2503.8 | 0.5 | 0.794 | 0.840 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 3.1623 | 6880.0 | 7580.8 | 2503.8 | 0.5 | 0.882 | 0.908 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 10.0 | 2870.0 | 7580.8 | 2503.8 | 1.0 | 0.089 | 0.379 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 10.0 | 2657.0 | 7580.8 | 2503.8 | 1.0 | 0.038 | 0.350 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 10.0 | 3320.0 | 7580.8 | 2503.8 | 1.0 | 0.193 | 0.438 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 10.0 | 3264.0 | 7580.8 | 2503.8 | 1.0 | 0.180 | 0.431 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 2 | 72 | 0.001 | 7913.0 | 7167.9 | 2409.0 | -3.0 | 1.130 | 1.100 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 0.001 | 7376.0 | 7167.9 | 2409.0 | -3.0 | 1.040 | 1.030 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 0.001 | 8049.0 | 7167.9 | 2409.0 | -3.0 | 1.150 | 1.120 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 0.001 | 7356.0 | 7167.9 | 2409.0 | -3.0 | 1.030 | 1.030 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 0.0032 | 7925.0 | 7167.9 | 2409.0 | -2.49 | 1.130 | 1.110 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 0.0032 | 7813.0 | 7167.9 | 2409.0 | -2.49 | 1.110 | 1.090 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 0.0032 | 6764.0 | 7167.9 | 2409.0 | -2.49 | 0.928 | 0.944 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 0.0032 | 7363.0 | 7167.9 | 2409.0 | -2.49 | 1.030 | 1.030 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 0.01 | 7209.0 | 7167.9 | 2409.0 | -2.0 | 1.010 | 1.010 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 0.01 | 7252.0 | 7167.9 | 2409.0 | -2.0 | 1.010 | 1.010 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 0.01 | 7772.0 | 7167.9 | 2409.0 | -2.0 | 1.110 | 1.080 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 0.01 | 6883.0 | 7167.9 | 2409.0 | -2.0 | 0.949 | 0.960 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 0.0316 | 6951.0 | 7167.9 | 2409.0 | -1.5 | 0.961 | 0.970 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 0.0316 | 7261.0 | 7167.9 | 2409.0 | -1.5 | 1.020 | 1.010 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 0.0316 | 7250.0 | 7167.9 | 2409.0 | -1.5 | 1.010 | 1.010 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 0.0316 | 7330.0 | 7167.9 | 2409.0 | -1.5 | 1.030 | 1.020 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 2 | 72 | 0.1 | 7219.0 | 7167.9 | 2409.0 | -1.0 | 1.010 | 1.010 | 1.573 | HCC70 QL-XII-61 0 2 |