Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | Torin2 | 3 | 72 | 0.1 | 2198.0 | 6533.6 | 1943.1 | -1.0 | 0.073 | 0.336 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 0.1 | 2142.0 | 6533.6 | 1943.1 | -1.0 | 0.057 | 0.328 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 0.1 | 2220.0 | 6533.6 | 1943.1 | -1.0 | 0.079 | 0.340 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 0.1 | 2501.0 | 6533.6 | 1943.1 | -1.0 | 0.155 | 0.383 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 0.3162 | 895.0 | 6533.6 | 1943.1 | -0.5 | -0.358 | 0.137 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 0.3162 | 779.0 | 6533.6 | 1943.1 | -0.5 | -0.407 | 0.119 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 0.3162 | 976.0 | 6533.6 | 1943.1 | -0.5 | -0.325 | 0.149 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 0.3162 | 856.0 | 6533.6 | 1943.1 | -0.5 | -0.374 | 0.131 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 1.0 | 236.0 | 6533.6 | 1943.1 | 0.0 | -0.700 | 0.036 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 1.0 | 244.0 | 6533.6 | 1943.1 | 0.0 | -0.695 | 0.037 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 1.0 | 255.0 | 6533.6 | 1943.1 | 0.0 | -0.687 | 0.039 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 1.0 | 284.0 | 6533.6 | 1943.1 | 0.0 | -0.667 | 0.044 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 3.1623 | 30.0 | 6533.6 | 1943.1 | 0.5 | -0.908 | 0.005 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 3.1623 | 40.0 | 6533.6 | 1943.1 | 0.5 | -0.891 | 0.006 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 3.1623 | 27.0 | 6533.6 | 1943.1 | 0.5 | -0.913 | 0.004 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 3.1623 | 33.0 | 6533.6 | 1943.1 | 0.5 | -0.903 | 0.005 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 10.0 | 15.0 | 6533.6 | 1943.1 | 1.0 | -0.938 | 0.002 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 10.0 | 7.0 | 6533.6 | 1943.1 | 1.0 | -0.960 | 0.001 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 10.0 | 21.0 | 6533.6 | 1943.1 | 1.0 | -0.925 | 0.003 | 1.750 | HCC70 Torin2 0 3 |
| HCC70 | Torin2 | 3 | 72 | 10.0 | 16.0 | 6533.6 | 1943.1 | 1.0 | -0.936 | 0.002 | 1.750 | HCC70 Torin2 0 3 |
| HCC1806 | AZD8055 | 1 | 72 | 0.001 | 16973.0 | 17793.8 | 2895.7 | -3.0 | 0.964 | 0.954 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 0.001 | 16989.0 | 17793.8 | 2895.7 | -3.0 | 0.965 | 0.955 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 0.001 | 16309.0 | 17793.8 | 2895.7 | -3.0 | 0.935 | 0.917 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 0.001 | 17216.0 | 17793.8 | 2895.7 | -3.0 | 0.975 | 0.968 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 0.0032 | 16634.0 | 17793.8 | 2895.7 | -2.49 | 0.949 | 0.935 | 2.619 | HCC1806 AZD8055 0 1 |