Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-X-138 | 3 | 72 | 0.0032 | 5733.0 | 6533.6 | 1943.1 | -2.49 | 0.856 | 0.877 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.0032 | 6894.0 | 6533.6 | 1943.1 | -2.49 | 1.060 | 1.060 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.0032 | 6877.0 | 6533.6 | 1943.1 | -2.49 | 1.060 | 1.050 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.01 | 6314.0 | 6533.6 | 1943.1 | -2.0 | 0.961 | 0.966 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.01 | 6445.0 | 6533.6 | 1943.1 | -2.0 | 0.984 | 0.986 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.01 | 6631.0 | 6533.6 | 1943.1 | -2.0 | 1.020 | 1.010 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.01 | 6022.0 | 6533.6 | 1943.1 | -2.0 | 0.909 | 0.922 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.0316 | 5677.0 | 6533.6 | 1943.1 | -1.5 | 0.846 | 0.869 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.0316 | 6788.0 | 6533.6 | 1943.1 | -1.5 | 1.040 | 1.040 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.0316 | 5802.0 | 6533.6 | 1943.1 | -1.5 | 0.869 | 0.888 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.0316 | 6826.0 | 6533.6 | 1943.1 | -1.5 | 1.050 | 1.040 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.1 | 5867.0 | 6533.6 | 1943.1 | -1.0 | 0.881 | 0.898 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.1 | 5880.0 | 6533.6 | 1943.1 | -1.0 | 0.883 | 0.900 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.1 | 6851.0 | 6533.6 | 1943.1 | -1.0 | 1.050 | 1.050 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.1 | 6492.0 | 6533.6 | 1943.1 | -1.0 | 0.993 | 0.994 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.3162 | 5327.0 | 6533.6 | 1943.1 | -0.5 | 0.780 | 0.815 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.3162 | 4962.0 | 6533.6 | 1943.1 | -0.5 | 0.709 | 0.759 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.3162 | 5756.0 | 6533.6 | 1943.1 | -0.5 | 0.860 | 0.881 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 0.3162 | 6049.0 | 6533.6 | 1943.1 | -0.5 | 0.914 | 0.926 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 1.0 | 4766.0 | 6533.6 | 1943.1 | 0.0 | 0.670 | 0.729 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 1.0 | 4635.0 | 6533.6 | 1943.1 | 0.0 | 0.644 | 0.709 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 1.0 | 5223.0 | 6533.6 | 1943.1 | 0.0 | 0.760 | 0.799 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 1.0 | 4784.0 | 6533.6 | 1943.1 | 0.0 | 0.674 | 0.732 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 3.1623 | 3392.0 | 6533.6 | 1943.1 | 0.5 | 0.375 | 0.519 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC70 | QL-X-138 | 3 | 72 | 3.1623 | 3089.0 | 6533.6 | 1943.1 | 0.5 | 0.303 | 0.473 | 1.750 | HCC70 QL-X-138 0 3 |