Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | ZSTK474 | 3 | 72 | 3.2 | 583.5 | 3579.5 | 586.9 | 0.505 | -0.002 | 0.163 | 2.609 | BT20 ZSTK474 0 3 |
| BT-549 | AS605240 | 1 | 72 | 0.001 | 5384.8 | 5429.5 | 1554.9 | -3.0 | 0.991 | 0.992 | 1.804 | BT549 AS605240 0 1 72 |
| BT-549 | AS605240 | 1 | 72 | 0.0032 | 5357.5 | 5429.5 | 1554.9 | -2.49 | 0.985 | 0.987 | 1.804 | BT549 AS605240 0 1 72 |
| BT-549 | AS605240 | 1 | 72 | 0.01 | 5341.5 | 5429.5 | 1554.9 | -2.0 | 0.982 | 0.984 | 1.804 | BT549 AS605240 0 1 72 |
| BT-549 | AS605240 | 1 | 72 | 0.032 | 5197.3 | 5429.5 | 1554.9 | -1.49 | 0.952 | 0.957 | 1.804 | BT549 AS605240 0 1 72 |
| BT-549 | AS605240 | 1 | 72 | 0.1 | 5340.5 | 5429.5 | 1554.9 | -1.0 | 0.982 | 0.984 | 1.804 | BT549 AS605240 0 1 72 |
| BT-549 | AS605240 | 1 | 72 | 0.32 | 5064.0 | 5429.5 | 1554.9 | -0.495 | 0.924 | 0.933 | 1.804 | BT549 AS605240 0 1 72 |
| BT-549 | AS605240 | 1 | 72 | 1.0 | 5082.5 | 5429.5 | 1554.9 | 0.0 | 0.928 | 0.936 | 1.804 | BT549 AS605240 0 1 72 |
| BT-549 | AS605240 | 1 | 72 | 3.2 | 4915.0 | 5429.5 | 1554.9 | 0.505 | 0.893 | 0.905 | 1.804 | BT549 AS605240 0 1 72 |
| BT-549 | AZD-6482 | 1 | 72 | 0.001 | 5306.0 | 5406.8 | 1554.9 | -3.0 | 0.979 | 0.981 | 1.798 | BT549 AZD6482 0 1 72 |
| BT-549 | AZD-6482 | 1 | 72 | 0.0032 | 5209.0 | 5406.8 | 1554.9 | -2.49 | 0.959 | 0.963 | 1.798 | BT549 AZD6482 0 1 72 |
| BT-549 | AZD-6482 | 1 | 72 | 0.01 | 5212.5 | 5406.8 | 1554.9 | -2.0 | 0.960 | 0.964 | 1.798 | BT549 AZD6482 0 1 72 |
| BT-549 | AZD-6482 | 1 | 72 | 0.032 | 5173.8 | 5406.8 | 1554.9 | -1.49 | 0.952 | 0.957 | 1.798 | BT549 AZD6482 0 1 72 |
| BT-549 | AZD-6482 | 1 | 72 | 0.1 | 4942.3 | 5406.8 | 1554.9 | -1.0 | 0.903 | 0.914 | 1.798 | BT549 AZD6482 0 1 72 |
| BT-549 | AZD-6482 | 1 | 72 | 0.32 | 4644.8 | 5406.8 | 1554.9 | -0.495 | 0.838 | 0.859 | 1.798 | BT549 AZD6482 0 1 72 |
| BT-549 | AZD-6482 | 1 | 72 | 1.0 | 4299.3 | 5406.8 | 1554.9 | 0.0 | 0.761 | 0.795 | 1.798 | BT549 AZD6482 0 1 72 |
| BT-549 | AZD-6482 | 1 | 72 | 3.2 | 3911.8 | 5406.8 | 1554.9 | 0.505 | 0.671 | 0.723 | 1.798 | BT549 AZD6482 0 1 72 |
| BT-549 | AZD8055 | 1 | 72 | 0.001 | 5177.5 | 5342.3 | 1554.9 | -3.0 | 0.965 | 0.969 | 1.781 | BT549 AZD8055 0 1 72 |
| BT-549 | AZD8055 | 1 | 72 | 0.0032 | 5004.5 | 5342.3 | 1554.9 | -2.49 | 0.928 | 0.937 | 1.781 | BT549 AZD8055 0 1 72 |
| BT-549 | AZD8055 | 1 | 72 | 0.01 | 4136.8 | 5342.3 | 1554.9 | -2.0 | 0.732 | 0.774 | 1.781 | BT549 AZD8055 0 1 72 |
| BT-549 | AZD8055 | 1 | 72 | 0.032 | 3250.8 | 5342.3 | 1554.9 | -1.49 | 0.513 | 0.608 | 1.781 | BT549 AZD8055 0 1 72 |
| BT-549 | AZD8055 | 1 | 72 | 0.1 | 2423.5 | 5342.3 | 1554.9 | -1.0 | 0.283 | 0.454 | 1.781 | BT549 AZD8055 0 1 72 |
| BT-549 | AZD8055 | 1 | 72 | 0.32 | 1896.5 | 5342.3 | 1554.9 | -0.495 | 0.118 | 0.355 | 1.781 | BT549 AZD8055 0 1 72 |
| BT-549 | AZD8055 | 1 | 72 | 1.0 | 2083.3 | 5342.3 | 1554.9 | 0.0 | 0.179 | 0.390 | 1.781 | BT549 AZD8055 0 1 72 |
| BT-549 | AZD8055 | 1 | 72 | 3.2 | 2039.5 | 5342.3 | 1554.9 | 0.505 | 0.165 | 0.382 | 1.781 | BT549 AZD8055 0 1 72 |