Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)

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Cell line Drug name Experimental replicate Timepoint Drug concentration Live cell count Average live cell count, DMSO control Average live cell count (time = 0) Log10(drug concentration) GR value Relative cell count (treatment versus DMSO) Cell doublings (DMSO control) Experiment name
BT-20 AS605240 1 72
0.001
5834.8 6371.0 1443.3
-3.0
0.920 0.916 2.142
BT20 AS605240 0 1
BT-20 AS605240 1 72
0.0032
6003.8 6371.0 1443.3
-2.49
0.945 0.942 2.142
BT20 AS605240 0 1
BT-20 AS605240 1 72
0.01
6095.5 6371.0 1443.3
-2.0
0.959 0.957 2.142
BT20 AS605240 0 1
BT-20 AS605240 1 72
0.032
5869.3 6371.0 1443.3
-1.49
0.925 0.921 2.142
BT20 AS605240 0 1
BT-20 AS605240 1 72
0.1
5634.5 6371.0 1443.3
-1.0
0.889 0.884 2.142
BT20 AS605240 0 1
BT-20 AS605240 1 72
0.32
5530.8 6371.0 1443.3
-0.495
0.872 0.868 2.142
BT20 AS605240 0 1
BT-20 AS605240 1 72
1.0
5369.8 6371.0 1443.3
0.0
0.847 0.843 2.142
BT20 AS605240 0 1
BT-20 AS605240 1 72
3.2
5187.0 6371.0 1443.3
0.505
0.817 0.814 2.142
BT20 AS605240 0 1
BT-20 AZD-6482 1 72
0.001
5532.3 5948.8 1443.3
-3.0
0.930 0.930 2.043
BT20 AZD6482 0 1
BT-20 AZD-6482 1 72
0.0032
5542.0 5948.8 1443.3
-2.49
0.932 0.932 2.043
BT20 AZD6482 0 1
BT-20 AZD-6482 1 72
0.01
5842.5 5948.8 1443.3
-2.0
0.982 0.982 2.043
BT20 AZD6482 0 1
BT-20 AZD-6482 1 72
0.032
5770.3 5948.8 1443.3
-1.49
0.970 0.970 2.043
BT20 AZD6482 0 1
BT-20 AZD-6482 1 72
0.1
5531.0 5948.8 1443.3
-1.0
0.930 0.930 2.043
BT20 AZD6482 0 1
BT-20 AZD-6482 1 72
0.32
5060.8 5948.8 1443.3
-0.495
0.848 0.851 2.043
BT20 AZD6482 0 1
BT-20 AZD-6482 1 72
1.0
3655.0 5948.8 1443.3
0.0
0.576 0.614 2.043
BT20 AZD6482 0 1
BT-20 AZD-6482 1 72
3.2
2032.7 5948.8 1443.3
0.505
0.182 0.342 2.043
BT20 AZD6482 0 1
BT-20 AZD8055 1 72
0.001
5501.0 5941.5 1443.3
-3.0
0.926 0.926 2.041
BT20 AZD8055 0 1
BT-20 AZD8055 1 72
0.0032
5387.5 5941.5 1443.3
-2.49
0.906 0.907 2.041
BT20 AZD8055 0 1
BT-20 AZD8055 1 72
0.01
4836.5 5941.5 1443.3
-2.0
0.808 0.814 2.041
BT20 AZD8055 0 1
BT-20 AZD8055 1 72
0.032
3968.5 5941.5 1443.3
-1.49
0.641 0.668 2.041
BT20 AZD8055 0 1
BT-20 AZD8055 1 72
0.1
2922.5 5941.5 1443.3
-1.0
0.413 0.492 2.041
BT20 AZD8055 0 1
BT-20 AZD8055 1 72
0.32
2468.3 5941.5 1443.3
-0.495
0.301 0.415 2.041
BT20 AZD8055 0 1
BT-20 AZD8055 1 72
1.0
2287.8 5941.5 1443.3
0.0
0.253 0.385 2.041
BT20 AZD8055 0 1
BT-20 AZD8055 1 72
3.2
2067.3 5941.5 1443.3
0.505
0.192 0.348 2.041
BT20 AZD8055 0 1
BT-20 Dactolisib 1 72
0.001
5363.3 5998.3 1443.3
-3.0
0.894 0.894 2.055
BT20 BEZ235 0 1
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