Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | AS605240 | 1 | 72 | 0.001 | 5834.8 | 6371.0 | 1443.3 | -3.0 | 0.920 | 0.916 | 2.142 | BT20 AS605240 0 1 |
| BT-20 | AS605240 | 1 | 72 | 0.0032 | 6003.8 | 6371.0 | 1443.3 | -2.49 | 0.945 | 0.942 | 2.142 | BT20 AS605240 0 1 |
| BT-20 | AS605240 | 1 | 72 | 0.01 | 6095.5 | 6371.0 | 1443.3 | -2.0 | 0.959 | 0.957 | 2.142 | BT20 AS605240 0 1 |
| BT-20 | AS605240 | 1 | 72 | 0.032 | 5869.3 | 6371.0 | 1443.3 | -1.49 | 0.925 | 0.921 | 2.142 | BT20 AS605240 0 1 |
| BT-20 | AS605240 | 1 | 72 | 0.1 | 5634.5 | 6371.0 | 1443.3 | -1.0 | 0.889 | 0.884 | 2.142 | BT20 AS605240 0 1 |
| BT-20 | AS605240 | 1 | 72 | 0.32 | 5530.8 | 6371.0 | 1443.3 | -0.495 | 0.872 | 0.868 | 2.142 | BT20 AS605240 0 1 |
| BT-20 | AS605240 | 1 | 72 | 1.0 | 5369.8 | 6371.0 | 1443.3 | 0.0 | 0.847 | 0.843 | 2.142 | BT20 AS605240 0 1 |
| BT-20 | AS605240 | 1 | 72 | 3.2 | 5187.0 | 6371.0 | 1443.3 | 0.505 | 0.817 | 0.814 | 2.142 | BT20 AS605240 0 1 |
| BT-20 | AZD-6482 | 1 | 72 | 0.001 | 5532.3 | 5948.8 | 1443.3 | -3.0 | 0.930 | 0.930 | 2.043 | BT20 AZD6482 0 1 |
| BT-20 | AZD-6482 | 1 | 72 | 0.0032 | 5542.0 | 5948.8 | 1443.3 | -2.49 | 0.932 | 0.932 | 2.043 | BT20 AZD6482 0 1 |
| BT-20 | AZD-6482 | 1 | 72 | 0.01 | 5842.5 | 5948.8 | 1443.3 | -2.0 | 0.982 | 0.982 | 2.043 | BT20 AZD6482 0 1 |
| BT-20 | AZD-6482 | 1 | 72 | 0.032 | 5770.3 | 5948.8 | 1443.3 | -1.49 | 0.970 | 0.970 | 2.043 | BT20 AZD6482 0 1 |
| BT-20 | AZD-6482 | 1 | 72 | 0.1 | 5531.0 | 5948.8 | 1443.3 | -1.0 | 0.930 | 0.930 | 2.043 | BT20 AZD6482 0 1 |
| BT-20 | AZD-6482 | 1 | 72 | 0.32 | 5060.8 | 5948.8 | 1443.3 | -0.495 | 0.848 | 0.851 | 2.043 | BT20 AZD6482 0 1 |
| BT-20 | AZD-6482 | 1 | 72 | 1.0 | 3655.0 | 5948.8 | 1443.3 | 0.0 | 0.576 | 0.614 | 2.043 | BT20 AZD6482 0 1 |
| BT-20 | AZD-6482 | 1 | 72 | 3.2 | 2032.7 | 5948.8 | 1443.3 | 0.505 | 0.182 | 0.342 | 2.043 | BT20 AZD6482 0 1 |
| BT-20 | AZD8055 | 1 | 72 | 0.001 | 5501.0 | 5941.5 | 1443.3 | -3.0 | 0.926 | 0.926 | 2.041 | BT20 AZD8055 0 1 |
| BT-20 | AZD8055 | 1 | 72 | 0.0032 | 5387.5 | 5941.5 | 1443.3 | -2.49 | 0.906 | 0.907 | 2.041 | BT20 AZD8055 0 1 |
| BT-20 | AZD8055 | 1 | 72 | 0.01 | 4836.5 | 5941.5 | 1443.3 | -2.0 | 0.808 | 0.814 | 2.041 | BT20 AZD8055 0 1 |
| BT-20 | AZD8055 | 1 | 72 | 0.032 | 3968.5 | 5941.5 | 1443.3 | -1.49 | 0.641 | 0.668 | 2.041 | BT20 AZD8055 0 1 |
| BT-20 | AZD8055 | 1 | 72 | 0.1 | 2922.5 | 5941.5 | 1443.3 | -1.0 | 0.413 | 0.492 | 2.041 | BT20 AZD8055 0 1 |
| BT-20 | AZD8055 | 1 | 72 | 0.32 | 2468.3 | 5941.5 | 1443.3 | -0.495 | 0.301 | 0.415 | 2.041 | BT20 AZD8055 0 1 |
| BT-20 | AZD8055 | 1 | 72 | 1.0 | 2287.8 | 5941.5 | 1443.3 | 0.0 | 0.253 | 0.385 | 2.041 | BT20 AZD8055 0 1 |
| BT-20 | AZD8055 | 1 | 72 | 3.2 | 2067.3 | 5941.5 | 1443.3 | 0.505 | 0.192 | 0.348 | 2.041 | BT20 AZD8055 0 1 |
| BT-20 | Dactolisib | 1 | 72 | 0.001 | 5363.3 | 5998.3 | 1443.3 | -3.0 | 0.894 | 0.894 | 2.055 | BT20 BEZ235 0 1 |