Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)
Small Molecules Studied
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- 24 Small Molecules
| HMS LINCS ID | Name | Alternative Names | LINCS ID | Structure Image | PubChem CID |
|---|---|---|---|---|---|
| 10007-1 | AZD8055 | LSM-1007 |  | 25262965 | |
| 10047-1 | Pictilisib | Pictrelisib; GDC-0941; RG-7321 | LSM-1047 |  | 17755052 |
| 10052-1 | Sirolimus | Rapamycin | LSM-1052 |  | 5040 |
| 10053-1 | ZSTK474 | LSM-1053 |  | 11647372 | |
| 10054-1 | AS605240 | LSM-42784 |  | 24906273 | |
| 10055-1 | BX-912 | LSM-1055 |  | 11754511 | |
| 10057-1 | MK2206 | LSM-1057 |  | 24964624 | |
| 10059-1 | AZD-6482 | KIN001-193 | LSM-1059 |  | 44137675 |
| 10064-1 | WYE-125132 | LSM-1064 |  | 25260757 | |
| 10079-1 | Torin1 | LSM-1079 |  | 49836027 | |
| 10080-1 | Torin2 | LSM-1080 |  | 51358113 | |
| 10081-1 | KIN001-244 | LSM-1081 |  | 49766501 | |
| 10126-1 | PI103 | LSM-1126 |  | 9884685 | |
| 10142-1 | Trametinib | GSK-1120212; GSK1120212; GSK1120212B; JTP-74057 | LSM-1143 |  | 11707110 |
| 10146-3 | Omipalisib | GSK2126458; GSK2126458A | LSM-1147 |  | 25167777 |
| 10147-1 | Buparlisib | BKM120; NVP-BKM120 | LSM-1148 |  | 16654980 |
| 10148-1 | XL147 | SAR245408 | LSM-1149 |  | 52914932 |
| 10171-1 | TGX221 | LSM-1172 |  | 9907093 | |
| 10190-1 | PIK-93 | LSM-1191 |  | 6852167 | |
| 10204-1 | CAL-101 | LSM-1205 |  | 11625818 | |
| 10232-1 | Dactolisib | BEZ235; NVP-BEZ235 | LSM-4255 |  | 11977753 |
| 10233-1 | Alpelisib | BYL719 | LSM-4256 |  | 56649450 |
| 10234-1 | GDC-0980 | RG7422 | LSM-4257 |  | 66694608 |
| 10235-1 | Everolimus | RAD001 | LSM-4258 |  | 53398658 |
- 24 Small Molecules