Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)
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Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
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Hs 578T | ZSTK474 | 3 | 72 | 0.01 | 4039.0 | 4157.8 | 571.3 | -2.0 | 0.980 | 0.971 | 2.863 | Hs578T ZSTK474 3 |
Hs 578T | ZSTK474 | 3 | 72 | 0.032 | 3808.3 | 4157.8 | 571.3 | -1.49 | 0.940 | 0.916 | 2.863 | Hs578T ZSTK474 3 |
Hs 578T | ZSTK474 | 3 | 72 | 0.1 | 3278.3 | 4157.8 | 571.3 | -1.0 | 0.841 | 0.788 | 2.863 | Hs578T ZSTK474 3 |
Hs 578T | ZSTK474 | 3 | 72 | 0.32 | 2537.5 | 4157.8 | 571.3 | -0.495 | 0.683 | 0.610 | 2.863 | Hs578T ZSTK474 3 |
Hs 578T | ZSTK474 | 3 | 72 | 1.0 | 1793.5 | 4157.8 | 571.3 | 0.0 | 0.491 | 0.431 | 2.863 | Hs578T ZSTK474 3 |
Hs 578T | ZSTK474 | 3 | 72 | 3.2 | 1237.3 | 4157.8 | 571.3 | 0.505 | 0.310 | 0.298 | 2.863 | Hs578T ZSTK474 3 |