Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | PIK-93 | 1 | 72 | 0.001 | 3556.8 | 3572.0 | 873.1 | -3.0 | 0.996 | 0.996 | 2.033 | Hs578T PIK93 1 |
| Hs 578T | PIK-93 | 1 | 72 | 0.0032 | 3503.8 | 3572.0 | 873.1 | -2.49 | 0.981 | 0.981 | 2.033 | Hs578T PIK93 1 |
| Hs 578T | PIK-93 | 1 | 72 | 0.01 | 3504.3 | 3572.0 | 873.1 | -2.0 | 0.981 | 0.981 | 2.033 | Hs578T PIK93 1 |
| Hs 578T | PIK-93 | 1 | 72 | 0.032 | 3367.0 | 3572.0 | 873.1 | -1.49 | 0.943 | 0.943 | 2.033 | Hs578T PIK93 1 |
| Hs 578T | PIK-93 | 1 | 72 | 0.1 | 3129.0 | 3572.0 | 873.1 | -1.0 | 0.874 | 0.876 | 2.033 | Hs578T PIK93 1 |
| Hs 578T | PIK-93 | 1 | 72 | 0.32 | 2670.3 | 3572.0 | 873.1 | -0.495 | 0.733 | 0.748 | 2.033 | Hs578T PIK93 1 |
| Hs 578T | PIK-93 | 1 | 72 | 1.0 | 2344.8 | 3572.0 | 873.1 | 0.0 | 0.626 | 0.656 | 2.033 | Hs578T PIK93 1 |
| Hs 578T | PIK-93 | 1 | 72 | 3.2 | 1432.3 | 3572.0 | 873.1 | 0.505 | 0.276 | 0.401 | 2.033 | Hs578T PIK93 1 |
| Hs 578T | Sirolimus | 1 | 72 | 0.001 | 2469.5 | 3525.0 | 873.1 | -3.0 | 0.676 | 0.701 | 2.013 | Hs578T Rapamycin 1 |
| Hs 578T | Sirolimus | 1 | 72 | 0.0032 | 2484.3 | 3525.0 | 873.1 | -2.49 | 0.681 | 0.705 | 2.013 | Hs578T Rapamycin 1 |
| Hs 578T | Sirolimus | 1 | 72 | 0.01 | 2431.5 | 3525.0 | 873.1 | -2.0 | 0.663 | 0.690 | 2.013 | Hs578T Rapamycin 1 |
| Hs 578T | Sirolimus | 1 | 72 | 0.032 | 2426.8 | 3525.0 | 873.1 | -1.49 | 0.662 | 0.688 | 2.013 | Hs578T Rapamycin 1 |
| Hs 578T | Sirolimus | 1 | 72 | 0.1 | 2357.5 | 3525.0 | 873.1 | -1.0 | 0.638 | 0.669 | 2.013 | Hs578T Rapamycin 1 |
| Hs 578T | Sirolimus | 1 | 72 | 0.32 | 2315.8 | 3525.0 | 873.1 | -0.495 | 0.623 | 0.657 | 2.013 | Hs578T Rapamycin 1 |
| Hs 578T | Sirolimus | 1 | 72 | 1.0 | 2212.0 | 3525.0 | 873.1 | 0.0 | 0.587 | 0.628 | 2.013 | Hs578T Rapamycin 1 |
| Hs 578T | Sirolimus | 1 | 72 | 3.2 | 2252.0 | 3525.0 | 873.1 | 0.505 | 0.601 | 0.639 | 2.013 | Hs578T Rapamycin 1 |
| Hs 578T | TGX221 | 1 | 72 | 0.001 | 3501.3 | 3538.5 | 873.1 | -3.0 | 0.990 | 0.989 | 2.019 | Hs578T TGX221 1 |
| Hs 578T | TGX221 | 1 | 72 | 0.0032 | 3450.0 | 3538.5 | 873.1 | -2.49 | 0.975 | 0.975 | 2.019 | Hs578T TGX221 1 |
| Hs 578T | TGX221 | 1 | 72 | 0.01 | 3495.8 | 3538.5 | 873.1 | -2.0 | 0.988 | 0.988 | 2.019 | Hs578T TGX221 1 |
| Hs 578T | TGX221 | 1 | 72 | 0.032 | 3381.0 | 3538.5 | 873.1 | -1.49 | 0.955 | 0.955 | 2.019 | Hs578T TGX221 1 |
| Hs 578T | TGX221 | 1 | 72 | 0.1 | 3258.8 | 3538.5 | 873.1 | -1.0 | 0.920 | 0.921 | 2.019 | Hs578T TGX221 1 |
| Hs 578T | TGX221 | 1 | 72 | 0.32 | 3079.0 | 3538.5 | 873.1 | -0.495 | 0.867 | 0.870 | 2.019 | Hs578T TGX221 1 |
| Hs 578T | TGX221 | 1 | 72 | 1.0 | 2869.0 | 3538.5 | 873.1 | 0.0 | 0.803 | 0.811 | 2.019 | Hs578T TGX221 1 |
| Hs 578T | TGX221 | 1 | 72 | 3.2 | 2506.5 | 3538.5 | 873.1 | 0.505 | 0.686 | 0.708 | 2.019 | Hs578T TGX221 1 |
| Hs 578T | Torin1 | 1 | 72 | 0.001 | 3297.5 | 3386.5 | 873.1 | -3.0 | 0.973 | 0.974 | 1.956 | Hs578T Torin1 1 |