Breast Cancer Profiling Project, Drug Sensitivity phase II: Fixed-cell GR measures of 33 breast cell lines and PDX lines to 16 small molecule perturbagens from library plate II. Dataset 2 of 2: Calculated dose response metrics - Dataset (ID:20355)
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| Cell | Small Molecule | GR50 | GRmax | GR_AOC | GEC50 | GRinf | GR Hill Coefficient | GR r2 | pval_GR |
|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | LY3023414 | 0.001300375 | 0.0271 | 0.7252 | 0.0029 | -0.0905 | 0.2088 | 0.9598 | 1.11e-16 |
| HCC1143 | LY3023414 | 0.280841078 | -0.2472 | 0.4301 | 9.5524 | -1.0000 | 0.3115 | 0.8676 | 1.05e-11 |
| AU565 | LY3023414 | 0.003983539 | -0.4704 | 0.7921 | 0.8999 | -1.0000 | 0.2027 | 0.8707 | 7.87e-12 |
| CAL-51 | LY3023414 | 0.012387901 | -0.1180 | 0.6129 | 29.3234 | -1.0000 | 0.1414 | 0.7984 | 2.03e-09 |
| HCC1937 | LY3023414 | 0.148759974 | -0.0889 | 0.4702 | 448.2987 | -1.0000 | 0.1371 | 0.5290 | 8.17e-05 |
| HCC70 | LY3023414 | 0.00246998519581 | -0.7413 | 0.7828 | 0.7825 | -1.0000 | 0.1908 | 0.6120 | 7.2607777184e-06 |
| SK-BR-3 | LY3023414 | 0.002156645 | -0.5571 | 0.8238 | 0.7182 | -1.0000 | 0.1891 | 0.7978 | 2.1e-09 |
| HCC1500 | LY3023414 | 2.44e-06 | -0.9965 | 1.9835 | 0.0000 | -0.9955 | 0.7773 | 0.6628 | 1.25e-06 |
| CAMA-1 | LY3023414 | 4.27e-05 | -0.5001 | 0.9375 | 0.0004 | -0.2985 | 0.2143 | 0.5057 | 0.00014946 |
| HCC1428 | LY3023414 | 4.66e-07 | -0.7374 | 1.2208 | 0.0032 | -1.0000 | 0.1242 | 0.3630 | 0.003559188 |
| MDA-MB-468 | LY3023414 | 0.012514366 | -0.2268 | 0.6656 | 5.3535 | -1.0000 | 0.1813 | 0.8899 | 1.05e-12 |
| SUM1315MO2 | LY3023414 | 0.016412717 | -0.2854 | 0.6641 | 4.0058 | -1.0000 | 0.1998 | 0.8425 | 9.21e-11 |
| MCF 10A | LY3023414 | 0.157364650671 | 0.0496 | 0.4399 | 0.1188 | 0.0589 | 0.4459 | 0.9485 | 1.11022302463e-16 |
| HCC70 | MK 1775 | 0.000494343213706 | -0.7213 | 1.1390 | 0.0113 | -0.7848 | 0.3020 | 0.9292 | 4.21884749358e-15 |
| HCC1806 | MK 1775 | 0.0128166062504 | -0.4617 | 0.8151 | 0.0380 | -0.4095 | 0.5503 | 0.9684 | 1.11022302463e-16 |
| BT-549 | MK 1775 | 0.285141860039 | -0.4630 | 0.4365 | 2.2824 | -1.0000 | 0.5282 | 0.9608 | 1.11022302463e-16 |
| MCF7 | MK 1775 | -inf | -0.1007 | ||||||
| SK-BR-3 | MK 1775 | 0.230887652 | -0.6053 | 0.5073 | 2.0221 | -1.0000 | 0.5063 | 0.8951 | 5.72e-13 |
| HCC1419 | MK 1775 | 2.452749667 | -0.0791 | 0.2879 | 12.3795 | -1.0000 | 0.6786 | 0.7916 | 3.06e-09 |
| MCF 10A | MK 1775 | 4.928502071 | -0.1207 | 0.1367 | 9.4221 | -1.0000 | 1.6953 | 0.9500 | 1.11e-16 |
| MDA-MB-436 | MK 1775 | 0.189831078 | -0.2473 | 0.4933 | 6.7449 | -1.0000 | 0.3077 | 0.8316 | 2.13e-10 |
| BT-20 | MK 1775 | 1.80498033053 | -0.6583 | 0.2015 | 4.1869 | -1.0000 | 1.3057 | 0.9322 | 2.44249065418e-15 |
| MDA-MB-453 | MK 1775 | 0.103540362 | -0.1845 | 0.5656 | 0.2626 | -0.3748 | 0.6010 | 0.9620 | 1.11e-16 |
| SUM149PT | MK 1775 | 0.07431046 | -0.3915 | 0.6115 | 1.7986 | -1.0000 | 0.3448 | 0.9622 | 1.11e-16 |
| AU565 | MK 1775 | 0.223405816 | -0.4543 | 0.4894 | 3.6482 | -1.0000 | 0.3933 | 0.8692 | 9.09e-12 |