Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HCC1143 Bleomycin
3.1623
Radiation
Misc
 -0.1654 0.37453
HCC1143 Bleomycin
10.0
Radiation
Misc
 -0.2085 0.43857
HCC1143 Ipatasertib
0.001
AKT
PI3K/mTOR
 0.9221 0.00021
HCC1143 Ipatasertib
0.0031623
AKT
PI3K/mTOR
 0.9761 -0.00258
HCC1143 Ipatasertib
0.01
AKT
PI3K/mTOR
 1.0017 -0.00291
HCC1143 Ipatasertib
0.031623
AKT
PI3K/mTOR
 0.9587 -0.00021
HCC1143 Ipatasertib
0.1
AKT
PI3K/mTOR
 0.9777 0.00590
HCC1143 Ipatasertib
0.31623
AKT
PI3K/mTOR
 0.9576 -0.00347
HCC1143 Ipatasertib
1.0
AKT
PI3K/mTOR
 0.8866 -0.00830
HCC1143 Ipatasertib
3.1623
AKT
PI3K/mTOR
 0.8757 -0.00725
HCC1143 Ipatasertib
10.0
AKT
PI3K/mTOR
 0.7509 -0.00186
HCC1143 Alpelisib
0.001
PI3Ka
PI3K/mTOR
 0.9020 0.00674
HCC1143 Alpelisib
0.0031623
PI3Ka
PI3K/mTOR
 0.9141 -0.00021
HCC1143 Alpelisib
0.01
PI3Ka
PI3K/mTOR
 0.9601 0.00381
HCC1143 Alpelisib
0.031623
PI3Ka
PI3K/mTOR
 0.8862 0.00665
HCC1143 Alpelisib
0.1
PI3Ka
PI3K/mTOR
 0.8885 0.00368
HCC1143 Alpelisib
0.31623
PI3Ka
PI3K/mTOR
 0.8526 0.01623
HCC1143 Alpelisib
1.0
PI3Ka
PI3K/mTOR
 0.7859 0.02360
HCC1143 Alpelisib
3.1623
PI3Ka
PI3K/mTOR
 0.6275 0.04074
HCC1143 Alpelisib
10.0
PI3Ka
PI3K/mTOR
 0.4797 0.06909
HCC1143 Taselisib
0.001
PI3Ka, g, d
PI3K/mTOR
 0.9011 0.00435
HCC1143 Taselisib
0.0031623
PI3Ka, g, d
PI3K/mTOR
 0.8640 0.01053
HCC1143 Taselisib
0.01
PI3Ka, g, d
PI3K/mTOR
 0.8138 0.02172
HCC1143 Taselisib
0.031623
PI3Ka, g, d
PI3K/mTOR
 0.6723 0.03849
HCC1143 Taselisib
0.1
PI3Ka, g, d
PI3K/mTOR
 0.5302 0.05386