Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HCC1143 A-1210477
0.001
Mcl-1
Misc
 0.9391 0.00022
HCC1143 A-1210477
0.0031623
Mcl-1
Misc
 0.9440 -0.00031
HCC1143 A-1210477
0.01
Mcl-1
Misc
 0.9545 -0.00519
HCC1143 A-1210477
0.031623
Mcl-1
Misc
 0.9471 -0.00290
HCC1143 A-1210477
0.1
Mcl-1
Misc
 1.0102 -0.00015
HCC1143 A-1210477
0.31623
Mcl-1
Misc
 0.9410 -0.00249
HCC1143 A-1210477
1.0
Mcl-1
Misc
 0.9910 -0.00169
HCC1143 A-1210477
3.1623
Mcl-1
Misc
 0.8944 0.00555
HCC1143 A-1210477
10.0
Mcl-1
Misc
 0.6719 0.01379
HCC1143 Olaparib
0.001
PARP
Misc
 0.9542 -0.00136
HCC1143 Olaparib
0.0031623
PARP
Misc
 1.0401 -0.00692
HCC1143 Olaparib
0.01
PARP
Misc
 0.9880 -0.00167
HCC1143 Olaparib
0.031623
PARP
Misc
 1.0011 0.00204
HCC1143 Olaparib
0.1
PARP
Misc
 0.9760 0.00646
HCC1143 Olaparib
0.31623
PARP
Misc
 0.9231 0.00165
HCC1143 Olaparib
1.0
PARP
Misc
 0.8713 0.00886
HCC1143 Olaparib
3.1623
PARP
Misc
 0.7555 0.02853
HCC1143 Olaparib
10.0
PARP
Misc
 0.4562 0.10427
HCC1143 Bleomycin
0.0010833
Radiation
Misc
 0.9742 0.00864
HCC1143 Bleomycin
0.0033333
Radiation
Misc
 0.9639 0.00779
HCC1143 Bleomycin
0.01
Radiation
Misc
 0.8819 0.03795
HCC1143 Bleomycin
0.031667
Radiation
Misc
 0.5830 0.10159
HCC1143 Bleomycin
0.1
Radiation
Misc
 0.3093 0.17413
HCC1143 Bleomycin
0.31623
Radiation
Misc
 -0.0401 0.28557
HCC1143 Bleomycin
1.0
Radiation
Misc
 -0.1369 0.33075